Literature DB >> 923405

Multiple mucosal neuroma (MMN) or multiple endocrine neoplasia (MEN) type 3 syndrome. Ocular manifestations: a case report.

N M Schweitzer, B A van der Pol.   

Abstract

Case report of a young man showing neuromas of the palpebral and bulbar conjunctiva and markedly thickened nerve fibers in both cornea. Multiple neuromas were seen on the lips and in the oral cavity. A medullary carcinoma of the thyroid was found. These symptoms pointed to the diagnosis of a MMN or MEN type 3 syndrome. There were no signs of phaeochromocytoma, however, which also belongs to this syndrome. The ophthalmologist, who may be the first to see such a patient as a child, should be aware of the malignancies which develop around puberty and of the strong and dominant heredity of this disease.

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Year:  1977        PMID: 923405     DOI: 10.1007/bf00171466

Source DB:  PubMed          Journal:  Doc Ophthalmol        ISSN: 0012-4486            Impact factor:   2.379


  7 in total

1.  Hypertrophy of peripheral nerves in the syndrome of multiple mucosal neuromas, endocrine tumours and Marfanoid habitus. Autonomic disturbances and sural nerve findings.

Authors:  E Joosten; A Gabreëls-Festen; M Horstink; F Gabreëls; H Jaspar; J Korten; H Vingerhoets
Journal:  Acta Neuropathol       Date:  1974       Impact factor: 17.088

2.  Multiple mucosal neuromas, pheochromocytoma, medullary carcinoma of the thyroid and marfanoid body build with muscle wasting. Syndrome of hyperplasia and neoplasia of neural crest derivatives--an unitarian concept.

Authors:  R J Gorlin; B L Mirkin
Journal:  Z Kinderheilkd       Date:  1972

Review 3.  The APUD cell concept and its implications in pathology.

Authors:  A G Pearse
Journal:  Pathol Annu       Date:  1974

4.  Clinical demonstrations.

Authors:  C M Velzeboer
Journal:  Ophthalmologica       Date:  1970       Impact factor: 3.250

5.  Mucosal neuroma, pheochromocytoma and medullary thyroid carcinoma: multiple endocrine neoplasia type 3.

Authors:  M R Khairi; R N Dexter; N J Burzynski; C C Johnston
Journal:  Medicine (Baltimore)       Date:  1975-03       Impact factor: 1.889

6.  Multiple mucosal neuromata with endocrine tumours: a syndrome allied to von Recklinghausen's disease.

Authors:  E D Williams; D J Pollock
Journal:  J Pathol Bacteriol       Date:  1966-01
  7 in total

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