Literature DB >> 9230109

The study of cell-death proteins in the outer mitochondrial membrane by chemical cross-linking.

S T Ali1, J R Coggins, H T Jacobs.   

Abstract

Chemical cross-linking was used to study the interactions of the anti-cell-death protein Bcl2 with other proteins in the outer mitochondrial membrane. Cross-linking of mitochondrial surface proteins produced a large Bcl2-containing complex (>200 kDa), and a Bcl2-derived peptide was shown to cross-link specifically with a mitochondrial protein identified by immunoblotting as Raf-1 kinase.

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Year:  1997        PMID： 9230109      PMCID： PMC1218563          DOI： 10.1042/bj3250321

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  14 in total

1.  Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1.

Authors:  H G Wang; S Takayama; U R Rapp; J C Reed
Journal:  Proc Natl Acad Sci U S A       Date:  1996-07-09       Impact factor: 11.205

Review 2.  Molecular thanatopsis: a discourse on the BCL2 family and cell death.

Authors:  E Yang; S J Korsmeyer
Journal:  Blood       Date:  1996-07-15       Impact factor: 22.113

3.  X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death.

Authors:  S W Muchmore; M Sattler; H Liang; R P Meadows; J E Harlan; H S Yoon; D Nettesheim; B S Chang; C B Thompson; S L Wong; S L Ng; S W Fesik
Journal:  Nature       Date:  1996-05-23       Impact factor: 49.962

4.  The native structure of the activated Raf protein kinase is a membrane-bound multi-subunit complex.

Authors:  M Wartmann; R J Davis
Journal:  J Biol Chem       Date:  1994-03-04       Impact factor: 5.157

5.  The Ras-related protein R-ras interacts directly with Raf-1 in a GTP-dependent manner.

Authors:  M Spaargaren; G A Martin; F McCormick; M J Fernandez-Sarabia; J R Bischoff
Journal:  Biochem J       Date:  1994-06-01       Impact factor: 3.857

6.  Bcl-x(L) forms an ion channel in synthetic lipid membranes.

Authors:  A J Minn; P Vélez; S L Schendel; H Liang; S W Muchmore; S W Fesik; M Fill; C B Thompson
Journal:  Nature       Date:  1997-01-23       Impact factor: 49.962

7.  Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes.

Authors:  S Krajewski; S Tanaka; S Takayama; M J Schibler; W Fenton; J C Reed
Journal:  Cancer Res       Date:  1993-10-01       Impact factor: 12.701

8.  The bcl-2 protein is inserted into the outer membrane but not into the inner membrane of rat liver mitochondria in vitro.

Authors:  M Nakai; A Takeda; M L Cleary; T Endo
Journal:  Biochem Biophys Res Commun       Date:  1993-10-15       Impact factor: 3.575

Review 9.  Regulation of lymphocyte survival by the bcl-2 gene family.

Authors:  S Cory
Journal:  Annu Rev Immunol       Date:  1995       Impact factor: 28.527

Review 10.  Apoptosis: molecular regulation of cell death.

Authors:  A J Hale; C A Smith; L C Sutherland; V E Stoneman; V L Longthorne; A C Culhane; G T Williams
Journal:  Eur J Biochem       Date:  1996-02-15
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  1 in total

1.  The conserved N-terminal BH4 domain of Bcl-2 homologues is essential for inhibition of apoptosis and interaction with CED-4.

Authors:  D C Huang; J M Adams; S Cory
Journal:  EMBO J       Date:  1998-02-16       Impact factor: 11.598
  1 in total

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