Literature DB >> 9228167

A biokinetic model for 137Cs.

D R Melo1, J L Lipsztein, C A Oliveira, D L Lundgren, B A Muggenburg, R A Guilmette.   

Abstract

An improved biokinetic model for 137Cs in humans was developed based on an analysis of data obtained from individuals internally contaminated during an accident in Goiania, Brazil, and other data. Seventeen children (ten girls and seven boys 1-10 y old), ten adolescents (four females and six males), and thirty adults, (fifteen females and fifteen males contaminated in the accident in Goiânia contributed to this study. 137Cs retention was determined through periodic measurements in a whole-body counter. In addition to the data on 137Cs retention from these individuals, data from a study on the metabolism of 137Cs in immature, adult, and aged Beagle dogs and data from the literature were used in the formulation of the 137Cs biokinetic model presented. Mathematically, the retention of cesium is described by three exponential terms, and the retention model is based on a step function of body weight. When the ICRP Publication 56 model for cesium was compared to the model suggested in this paper, it was determined that the ICRP model predicts lower effective doses in 5-y-old children and higher effective doses in infants, adolescents, and adults.

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Year:  1997        PMID: 9228167     DOI: 10.1097/00004032-199708000-00004

Source DB:  PubMed          Journal:  Health Phys        ISSN: 0017-9078            Impact factor:   1.316


  8 in total

1.  Early alterations in cytokine expression in adult compared to developing lung in mice after radiation exposure.

Authors:  Carl J Johnston; Eric Hernady; Christina Reed; Sally W Thurston; Jacob N Finkelstein; Jacqueline P Williams
Journal:  Radiat Res       Date:  2010-04       Impact factor: 2.841

2.  Ribosome association and stability of the nascent polypeptide-associated complex is dependent upon its own ubiquitination.

Authors:  Olesya O Panasenko; Fabrice P A David; Martine A Collart
Journal:  Genetics       Date:  2008-12-15       Impact factor: 4.562

3.  Gene expression response of mice after a single dose of 137CS as an internal emitter.

Authors:  Sunirmal Paul; Shanaz A Ghandhi; Waylon Weber; Melanie Doyle-Eisele; Dunstana Melo; Raymond Guilmette; Sally A Amundson
Journal:  Radiat Res       Date:  2014-08-27       Impact factor: 2.841

4.  Dose and Dose-Rate Effects in a Mouse Model of Internal Exposure from 137Cs. Part 2: Integration of Gamma-H2AX and Gene Expression Biomarkers for Retrospective Radiation Biodosimetry.

Authors:  Igor Shuryak; Shanaz A Ghandhi; Helen C Turner; Waylon Weber; Dunstana Melo; Sally A Amundson; David J Brenner
Journal:  Radiat Res       Date:  2020-11-01       Impact factor: 2.841

5.  Whole-Body Counter Evaluation of Internal Radioactive Cesium in Dogs and Cats Exposed to the Fukushima Nuclear Disaster.

Authors:  Seiichi Wada; Nobuhiko Ito; Masamichi Watanabe; Takehiko Kakizaki; Masahiro Natsuhori; Jun Kawamata; Yoshio Urayama
Journal:  PLoS One       Date:  2017-01-18       Impact factor: 3.240

6.  Effect of dose and dose rate on temporal γ-H2AX kinetics in mouse blood and spleen mononuclear cells in vivo following Cesium-137 administration.

Authors:  Helen C Turner; Younghyun Lee; Waylon Weber; Dunstana Melo; Aimee Kowell; Shanaz A Ghandhi; Sally A Amundson; David J Brenner; Igor Shuryak
Journal:  BMC Mol Cell Biol       Date:  2019-05-28

7.  γ-H2AX Kinetic Profile in Mouse Lymphocytes Exposed to the Internal Emitters Cesium-137 and Strontium-90.

Authors:  Helen C Turner; Igor Shuryak; Waylon Weber; Melanie Doyle-Eisele; Dunstana Melo; Raymond Guilmette; Sally A Amundson; David J Brenner
Journal:  PLoS One       Date:  2015-11-30       Impact factor: 3.240

Review 8.  Medical Therapy of Patients Contaminated with Radioactive Cesium or Iodine.

Authors:  Jan Aaseth; Valeria Marina Nurchi; Ole Andersen
Journal:  Biomolecules       Date:  2019-12-11
  8 in total

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