Literature DB >> 922796

An in vivo stathmokinetic study of cell proliferation in human gastric carcinoma and gastric mucosa.

N A Wright, D C Britton, G Bone, D R Appleton.   

Abstract

Cell production rates were studied in a group of eleven patients with carcinoma of the stomach using an in vivo technique with vincristine. In normal pyloric mucosa estimates ranged from 8 to 15 cells/1000 cells/hr, and in the carcinomas from 3 to 24 cells/1000 cells/hr. Because of the very large variation in the data, comparison between individual tumours and normal mucosa is not regarded as being worth-while at this stage. The implications of these results for previous human in vivo stathmokinetic experiments are also discussed.

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Year:  1977        PMID: 922796     DOI: 10.1111/j.1365-2184.1977.tb00861.x

Source DB:  PubMed          Journal:  Cell Tissue Kinet        ISSN: 0008-8730


  5 in total

1.  Cell kinetics of human gastric mucosa and gastric cancer in organ culture.

Authors:  N Zafar; J C Macartney
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1991

Review 2.  Cell proliferation in gastrointestinal mucosa.

Authors:  W M Wong; N A Wright
Journal:  J Clin Pathol       Date:  1999-05       Impact factor: 3.411

3.  Validation of organ culture in colonic adaptation to surgical manipulation.

Authors:  G V Appleton; E E Wheeler; D N Challacombe; R C Williamson
Journal:  Gut       Date:  1991-09       Impact factor: 23.059

4.  The stathmokinetic (mitostatic) effect of vincristine and vinblastine on human gliomas.

Authors:  T Hoshino; C B Wilson; I Muraoka
Journal:  Acta Neuropathol       Date:  1979-06-15       Impact factor: 17.088

5.  Morphological studies on the long-term organ culture of colonic mucosa from normal and dimethylhydrazine treated rats.

Authors:  P V Senior; J P Sunter; D R Appleton; A J Watson
Journal:  Br J Cancer       Date:  1984-03       Impact factor: 7.640

  5 in total

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