Literature DB >> 9226395

Transforming growth factor alpha-immunoreactivity in neural tissues of the rat stomach.

P Hoffmann1, J M Zeeh, J Lakshmanan, L Liu, D Cooray, L Barajas, V E Eysselein.   

Abstract

We report TGF alpha immunoreactivity in neurons of the myenteric plexus and in nerve fibers in the muscle and submucosal layers of the rat stomach. Association of TGF alpha staining nerve fibers to vessels and smooth muscle cells gives morphological evidence that EGF/TGF alpha's actions to increase mucosal blood flow and gastric motility may be mediated by TGF alpha derived from neural structures. These data suggest that TGF alpha plays a role in the neural control of the gastric function.

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Year:  1997        PMID: 9226395     DOI: 10.1016/s0167-0115(97)02131-9

Source DB:  PubMed          Journal:  Regul Pept        ISSN: 0167-0115


  2 in total

Review 1.  Neuroimmune alterations of ENS functioning.

Authors:  L Bueno
Journal:  Gut       Date:  2000-12       Impact factor: 23.059

2.  Carbachol induces TGF-alpha expression and colonic epithelial cell proliferation in sensory-desensitised rats.

Authors:  Kerem Bulut; Peter Felderbauer; Karoline Hoeck; Wolfgang E Schmidt; Peter Hoffmann
Journal:  Int J Colorectal Dis       Date:  2009-12-10       Impact factor: 2.571

  2 in total

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