| Literature DB >> 9224803 |
Y Hara1, Y Ueta, T Isse, N Kabashima, I Shibuya, Y Hattori, H Yamashita.
Abstract
The effects of dehydration and food deprivation on urocortin-like immunoreactivity (Ucn-IR) in the rat supraoptic nucleus (SON) and the paraventricular nucleus (PVN) were examined by immunohistochemistry. Water deprivation for 48 h caused a significant increase in the number of Ucn-IR neurons in the SON, compared with control. Ucn-IR fibers and varicosities in the SON and the internal zone of the median eminence (ME) were increased, but a few and faint Ucn-IR neurons and fibers were observed in the PVN. On the other hand, food deprivation for 48 h caused a significant decrease in the number of Ucn-IR neurons in the SON, compared with control. Ucn-IR fibers and varicosities in the SON and the ME were fewer than those in controls. Ucn-IR neurons and fibers in the PVN were not detected after food deprivation. These results suggest that Ucn in the SON may be involved in the central regulation of water balance and nutrient homeostasis.Entities:
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Year: 1997 PMID： 9224803 DOI： 10.1016/s0304-3940(97)00419-9
Source DB: PubMed Journal: Neurosci Lett ISSN： 0304-3940 Impact factor: 3.046