Literature DB >> 9224538

Neurofibrillary pathology in the human paraventricular and supraoptic nuclei.

C Schultz1, E Ghebremedhin, H Braak, E Braak.   

Abstract

Severe neurofibrillary changes were identified in the paraventricular and supraoptic nuclei of elderly individuals using markers for Alzheimer's disease-related intraneuronal pathology. This neurofibrillary pathology is remarkable in that the magnocellular paraventricular and supraoptic nuclei are particularly resistant to Alzheimer's disease. Moreover, the changes were observed even in non-demented controls, indicating that they develop independently of Alzheimer's disease. The alterations in the paraventricular and supraoptic nuclei were consistently accompanied by neurofibrillary changes in the mediobasal hypothalamus.

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Year:  1997        PMID： 9224538     DOI： 10.1007/s004010050679

Source DB:  PubMed          Journal:  Acta Neuropathol        ISSN： 0001-6322            Impact factor:   17.088


  4 in total

1.  A Cross-Sectional Analysis of Late-Life Cardiovascular Factors and Their Relation to Clinically Defined Neurodegenerative Diseases.

Authors:  Brittany N Dugger; Michael Malek-Ahmadi; Sarah E Monsell; Walter A Kukull; Bryan K Woodruff; Eric M Reiman; Thomas G Beach; Jeffrey Wilson
Journal:  Alzheimer Dis Assoc Disord       Date:  2016 Jul-Sep       Impact factor: 2.703

2.  Hippocampal Sclerosis but Not Normal Aging or Alzheimer Disease Is Associated With TDP-43 Pathology in the Basal Forebrain of Aged Persons.

Authors:  Matthew D Cykowski; Hidehiro Takei; Linda J Van Eldik; Frederick A Schmitt; Gregory A Jicha; Suzanne Z Powell; Peter T Nelson
Journal:  J Neuropathol Exp Neurol       Date:  2016-03-12       Impact factor: 3.685

3.  TDP-43 pathology in the basal forebrain and hypothalamus of patients with amyotrophic lateral sclerosis.

Authors:  Matthew D Cykowski; Hidehiro Takei; Paul E Schulz; Stanley H Appel; Suzanne Z Powell
Journal:  Acta Neuropathol Commun       Date:  2014-12-24       Impact factor: 7.801

4.  Alzheimer disease neuropathology: understanding autonomic dysfunction.

Authors:  Eliasz Engelhardt; Jerson Laks
Journal:  Dement Neuropsychol       Date:  2008 Jul-Sep
  4 in total

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