Literature DB >> 9223523

Upregulation of human immunodeficiency virus (HIV) replication by CD4 cross-linking in peripheral blood mononuclear cells of HIV-infected adults.

S Than1, N Oyaizu, S Tetali, J Romano, M Kaplan, S Pahwa.   

Abstract

This study was conducted with peripheral blood mononuclear cells from 67 human immunodeficiency virus (HIV)-infected adults. It supports the hypothesis that cross-linking of CD4 molecules by HIV gp120 can result in HIV upregulation and spread of infection. Underlying mechanisms include activation of latent infection by factors in addition to, or other than, tumor necrosis factor alpha.

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Year:  1997        PMID： 9223523      PMCID： PMC191889     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  16 in total

1.  Activation of HIV expression by CD30 triggering in CD4+ T cells from HIV-infected individuals.

Authors:  E Maggi; F Annunziato; R Manetti; R Biagiotti; M G Giudizi; A Ravina; F Almerigogna; N Boiani; M Alderson; S Romagnani
Journal:  Immunity       Date:  1995-08       Impact factor: 31.745

2.  TCR cross-linking induces CTL death via internal action of TNF.

Authors:  J Wang; S A Stohlman; G Dennert
Journal:  J Immunol       Date:  1994-04-15       Impact factor: 5.422

3.  An inducible transcription factor activates expression of human immunodeficiency virus in T cells.

Authors:  G Nabel; D Baltimore
Journal:  Nature       Date:  1987 Apr 16-22       Impact factor: 49.962

4.  Cytokine pattern in relation to disease progression in human immunodeficiency virus-infected children.

Authors:  S Than; R Hu; N Oyaizu; J Romano; X Wang; S Sheikh; S Pahwa
Journal:  J Infect Dis       Date:  1997-01       Impact factor: 5.226

5.  Functional epitope analysis of the human CD4 molecule: antibodies that inhibit human immunodeficiency virus type 1 gene expression bind to the immunoglobulin CDR3-like region of CD4.

Authors:  M Benkirane; M Hirn; D Carrière; C Devaux
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103

6.  Signals transduced through the CD4 molecule on T lymphocytes activate NF-kappa B.

Authors:  N Chirmule; V S Kalyanaraman; S Pahwa
Journal:  Biochem Biophys Res Commun       Date:  1994-08-30       Impact factor: 3.575

7.  Human immunodeficiency virus type 1 RNA detection in peripheral blood mononuclear cells by polymerase chain reaction: enhanced sensitivity after mitogenic stimulation.

Authors:  S K Tetali; N Oyaizu; M Paul; S Pahwa
Journal:  AIDS Res Hum Retroviruses       Date:  1993-01       Impact factor: 2.205

8.  Viral dynamics in human immunodeficiency virus type 1 infection.

Authors:  X Wei; S K Ghosh; M E Taylor; V A Johnson; E A Emini; P Deutsch; J D Lifson; S Bonhoeffer; M A Nowak; B H Hahn
Journal:  Nature       Date:  1995-01-12       Impact factor: 49.962

9.  Cross-linking of CD4 molecules upregulates Fas antigen expression in lymphocytes by inducing interferon-gamma and tumor necrosis factor-alpha secretion.

Authors:  N Oyaizu; T W McCloskey; S Than; R Hu; V S Kalyanaraman; S Pahwa
Journal:  Blood       Date:  1994-10-15       Impact factor: 22.113

10.  Association of p56lck with the cytoplasmic domain of CD4 modulates HIV-1 expression.

Authors:  M Tremblay; S Meloche; S Gratton; M A Wainberg; R P Sékaly
Journal:  EMBO J       Date:  1994-02-15       Impact factor: 11.598
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  2 in total

1.  Recombinant interleukin-16 selectively modulates surface receptor expression and cytokine release in macrophages and dendritic cells.

Authors:  E Hermann; E Darcissac; T Idziorek; A Capron; G M Bahr
Journal:  Immunology       Date:  1999-06       Impact factor: 7.397

2.  The protein tyrosine kinase p56lck is required for triggering NF-kappaB activation upon interaction of human immunodeficiency virus type 1 envelope glycoprotein gp120 with cell surface CD4.

Authors:  L Briant; V Robert-Hebmann; C Acquaviva; A Pelchen-Matthews; M Marsh; C Devaux
Journal:  J Virol       Date:  1998-07       Impact factor: 5.103
  2 in total

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