PURPOSE: To report the clinicopathologic findings of a myxoma that arose in the subepithelial region of the right cornea of a 53-year-old man 4 years after successful treatment of an infectious corneal ulcer. METHODS: Histopathologic and histochemical evaluation of corneal tissue. RESULTS: This rare lesion appears to have originated from corneal stromal fibroblasts that reacted to an inflammatory stimulus and produced excessive amounts of glycosaminoglycans (hyaluronic acid) rather than normal collagen. CONCLUSION: Myxoma formation may require interruption of Bowman's layer and proximity of the scar to the epithelium.
PURPOSE: To report the clinicopathologic findings of a myxoma that arose in the subepithelial region of the right cornea of a 53-year-old man 4 years after successful treatment of an infectious corneal ulcer. METHODS: Histopathologic and histochemical evaluation of corneal tissue. RESULTS: This rare lesion appears to have originated from corneal stromal fibroblasts that reacted to an inflammatory stimulus and produced excessive amounts of glycosaminoglycans (hyaluronic acid) rather than normal collagen. CONCLUSION:Myxoma formation may require interruption of Bowman's layer and proximity of the scar to the epithelium.
Authors: Bader S Al-Qahtani; Hind M Alkatan; Rajiv Khandekar; Ahmed Al-Salem; Samar A Al-Swailem Journal: Sci Rep Date: 2022-07-01 Impact factor: 4.996