Literature DB >> 9218009

Prognostic significance of tumour markers in endometrial cancer.

S S Lo1, D K Cheng, T Y Ng, L C Wong, H Y Ngan.   

Abstract

Serum cancer antigen (CA) 125, CA15.3, CA19.9, carcinoembryonic antigen and tissue polypeptide antigen were analyzed in 100 normal subjects, 47 patients with benign gynaecological diseases and 97 patients with endometrial cancer. The incidence of individual elevated tumour markers (> 2SD) was 21.5-30.9% in cancer patients. Elevations of CA125 and CA15.3 were significantly associated with poor prognostic clinical factors. Univariate anaylses showed that elevated CA125, CA15.3 and CA19.9 were significantly associated with shorter survival. In multivariate analysis, CA15.3 was highly significant and had a larger hazard ratio. In conclusion, CA15.3 is a useful marker for the prognosis of patients with endometrial cancer.

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Year:  1997        PMID: 9218009     DOI: 10.1159/000218037

Source DB:  PubMed          Journal:  Tumour Biol        ISSN: 1010-4283


  9 in total

1.  Serum carcinoembryonic antigen as a tumour marker in patients with endometrial cancer.

Authors:  Y Hashiguchi; M Kasai; T Fukuda; T Ichimura; T Yasui; T Sumi
Journal:  Curr Oncol       Date:  2016-10-25       Impact factor: 3.677

2.  Development of multimarker panel for early detection of endometrial cancer. High diagnostic power of prolactin.

Authors:  Zoya Yurkovetsky; Shlomo Ta'asan; Steve Skates; Alex Rand; Aleksey Lomakin; Faina Linkov; Adele Marrangoni; Lyudmila Velikokhatnaya; Matthew Winans; Elieser Gorelik; G Larry Maxwell; Karen Lu; Anna Lokshin
Journal:  Gynecol Oncol       Date:  2007-07-19       Impact factor: 5.482

3.  Serum Sialyl-Tn (STN) as a Tumor Marker in Patients with Endometrial Cancer.

Authors:  Yasunori Hashiguchi; Mari Kasai; Takeshi Fukuda; Tomoyuki Ichimura; Tomoyo Yasui; Toshiyuki Sumi
Journal:  Pathol Oncol Res       Date:  2015-12-17       Impact factor: 3.201

4.  Prognostic significance of gamma-glutamyltransferase in patients with endometrial cancer: a multi-centre trial.

Authors:  V Seebacher; S Polterauer; C Grimm; J Rahhal; G Hofstetter; E-M Bauer; H Husslein; H Leipold; C Marth; A Reinthaller; N Concin
Journal:  Br J Cancer       Date:  2012-02-07       Impact factor: 7.640

5.  Determination of CA-125 levels in the serum, cervical and vaginal secretions, and endometrium in Chinese women with precancerous disease or endometrial cancer.

Authors:  Shu-Ming He; Fuqi Xing; Hong Sui; Youming Wu; Yongli Wang; Dong Wang; Guanghui Chen; Zijing Kong; Shu-Feng Zhou
Journal:  Med Sci Monit       Date:  2011-11

6.  Multivariate Analysis of Prognostic Biomarkers in Surgically Treated Endometrial Cancer.

Authors:  Jianpei Li; Jianhua Lin; Yaoling Luo; Miaohuan Kuang; Yijun Liu
Journal:  PLoS One       Date:  2015-06-24       Impact factor: 3.240

7.  Serum biomarkers for early detection of gynecologic cancers.

Authors:  Yutaka Ueda; Takayuki Enomoto; Toshihiro Kimura; Takashi Miyatake; Kiyoshi Yoshino; Masami Fujita; Tadashi Kimura
Journal:  Cancers (Basel)       Date:  2010-06-14       Impact factor: 6.639

8.  The prognostic significance of preoperative serum cancer antigen 15-3 levels in endometrial carcinomas.

Authors:  Emre E Tas; Ayse F Yavuz
Journal:  Saudi Med J       Date:  2017-11       Impact factor: 1.484

Review 9.  The Complementary Role of Imaging and Tumor Biomarkerszzm321990in Gynecological Cancers: An Update of the Literature

Authors:  Emanuela Anastasi; Silvia Gigli; Laura Ballesio; Antonio Angeloni; Lucia Manganaro
Journal:  Asian Pac J Cancer Prev       Date:  2018-02-26
  9 in total

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