Literature DB >> 9217704

Protective effect of Trypanosoma rangeli against infections with a highly virulent strain of Trypanosoma cruzi.

C Zuñiga1, T Palau, P Penin, C Gamallo, J A de Diego.   

Abstract

We investigated the protective effect of Trypanosoma rangeli against infection with Trypanosoma cruzi in animal models of various ages and with different doses of inoculum. The age of the mice and the dose of parasites determined the course of the infection. When T. cruzi was inoculated into mice after challenge with T. rangeli, parasitaemia was more controlled, mortality decreased and histopathology showed lower inflammatory infiltration and pseudocysts. This study proposes a new murine model of the protective effect of recombinant proteins of T. rangeli for possible application in the vaccines field.

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Year:  1997        PMID： 9217704

Source DB:  PubMed          Journal:  Trop Med Int Health        ISSN： 1360-2276            Impact factor:   2.622


  8 in total

Review 1.  Advances and challenges towards a vaccine against Chagas disease.

Authors:  Israel Quijano-Hernandez; Eric Dumonteil
Journal:  Hum Vaccin       Date:  2011-11-01

Review 2.  Modulation of immune response in experimental Chagas disease.

Authors:  Beatriz Basso
Journal:  World J Exp Med       Date:  2013-02-20

3.  Different serological cross-reactivity of Trypanosoma rangeli forms in Trypanosoma cruzi-infected patients sera.

Authors:  Milene H de Moraes; Alessandra A Guarneri; Fabiana P Girardi; Juliana B Rodrigues; Iriane Eger; Kevin M Tyler; Mário Steindel; Edmundo C Grisard
Journal:  Parasit Vectors       Date:  2008-07-08       Impact factor: 3.876

4.  Vaccination of dogs with Trypanosoma rangeli induces antibodies against Trypanosoma cruzi in a rural area of Córdoba, Argentina.

Authors:  Beatriz Basso; Vanina Marini; Diego Gauna; Maria Frias
Journal:  Mem Inst Oswaldo Cruz       Date:  2016-04       Impact factor: 2.743

Review 5.  American trypanosomiasis, or Chagas disease, in Panama: a chronological synopsis of ecological and epidemiological research.

Authors:  Indra G Rodriguez; Jose R Loaiza
Journal:  Parasit Vectors       Date:  2017-10-10       Impact factor: 3.876

Review 6.  Precision Health for Chagas Disease: Integrating Parasite and Host Factors to Predict Outcome of Infection and Response to Therapy.

Authors:  Santiago J Martinez; Patricia S Romano; David M Engman
Journal:  Front Cell Infect Microbiol       Date:  2020-05-08       Impact factor: 6.073

7.  Vaccination with Trypanosoma rangeli reduces the infectiousness of dogs experimentally infected with Trypanosoma cruzi.

Authors:  Beatriz Basso; Irma Castro; Virginia Introini; Patricia Gil; Carine Truyens; Edgardo Moretti
Journal:  Vaccine       Date:  2007-03-08       Impact factor: 3.641

8.  Comparative Analysis of the Secretome and Interactome of Trypanosoma cruzi and Trypanosoma rangeli Reveals Species Specific Immune Response Modulating Proteins.

Authors:  Renata Watanabe Costa; Marina Ferreira Batista; Isabela Meneghelli; Ramon Oliveira Vidal; Carlos Alcides Nájera; Ana Clara Mendes; Izabela Augusta Andrade-Lima; José Franco da Silveira; Luciano Rodrigo Lopes; Ludmila Rodrigues Pinto Ferreira; Fernando Antoneli; Diana Bahia
Journal:  Front Immunol       Date:  2020-08-27       Impact factor: 7.561
  8 in total

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