Literature DB >> 9217065

Cloning and sequencing of the cellular-viral junctions from the human adenovirus type 5 transformed 293 cell line.

N Louis1, C Evelegh, F L Graham.   

Abstract

The human-viral junctions of integrated adenovirus type 5 (Ad5) DNA in 293 cells have been cloned and sequenced. The Ad5 sequences extend from nucleotides (nt) 1 to 4344 and are located in the pregnancy-specific beta-1-glycoprotein 4 (PSG 4) gene. This maps the insertion of Ad5 DNA to human chromosome 19 (19q13.2). The Ad5 sequences are represented as a single collinear insertion of viral DNA with no rearrangements. There were 19 bp of PSG4 DNA deleted at the site of insertion and an extra 3 nt (GTC) at the left viral/cellular junction. A short patch of homology between viral DNA and PSG4 DNA (6 nt with 1 mismatch) was present at the right junction.

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Year:  1997        PMID： 9217065     DOI： 10.1006/viro.1997.8597

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  61 in total

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3.  Common structure of rare replication-deficient E1-positive particles in adenoviral vector batches.

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4.  Recombinant adeno-associated viral vector production and purification.

Authors:  Jin-Hong Shin; Yongping Yue; Dongsheng Duan
Journal:  Methods Mol Biol       Date:  2012

5.  Adenovirus E1A proteins are closely associated with chromatin in productively infected and transformed cells.

Authors:  Maurice Green; Ninder K Panesar; Paul M Loewenstein
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6.  Promoter- and cell-specific transcriptional transactivation by the Kaposi's sarcoma-associated herpesvirus ORF57/Mta protein.

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7.  A new complementing cell line for replication-incompetent E1-deleted adenovirus propagation.

Authors:  Qingfu Xu; Maria T Arevalo; Michael E Pichichero; Mingtao Zeng
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8.  Induced pluripotent stem cells generated without viral integration.

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Review 9.  Factors modulating expression of Renilla luciferase from control plasmids used in luciferase reporter gene assays.

Authors:  Amde Selassie Shifera; John A Hardin
Journal:  Anal Biochem       Date:  2009-09-27       Impact factor: 3.365

10.  Inhibition of hypoxia-inducible factor-1alpha (HIF-1alpha) protein synthesis by DNA damage inducing agents.

Authors:  Jessica Jie Wei Lou; Yee Liu Chua; Eng Hui Chew; Jie Gao; Martin Bushell; Thilo Hagen
Journal:  PLoS One       Date:  2010-05-07       Impact factor: 3.240
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