| Literature DB >> 9216112 |
R M de Freitas1, M de A Faria, S N Alves, A L de Melo.
Abstract
The effects of ivermectin, a semi-synthetic drug widely used for treatment of livestock parasite diseases, were observed on Culex quinquefasciatus larvae. Toxic effects and mortality evaluation were carried out after 5, 15, 30 and 60 minutes of exposure to 1, 5 or 10 ppm of ivermectin solutions. Observations were made 24 and 48 hours after the beginning of the experiment, and loss of mobility, progressive paralysis and high mortality of larvae were recorded. The observed effects of ivermectin on the mosquito larvae is probably correlated with chloride channel activation on cell membranes.Entities:
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Year: 1996 PMID： 9216112 DOI： 10.1590/s0036-46651996000400010
Source DB: PubMed Journal: Rev Inst Med Trop Sao Paulo ISSN： 0036-4665 Impact factor: 1.846