| Literature DB >> 9214731 |
M Kako1, T Miura, Y Nishiyama, M Ichimaru, M Moriyasu, A Kato.
Abstract
Four triterpenoid glycosides isolated from the rhizomes of Polygala senega var. latifolia, senegins II-IV (1-3) and desmethoxysenegin II (4), were tested for hypoglycemic activity in normal and KK-Ay mice. Compounds 1 and 2 reduced the blood glucose of normal mice 4 h after intraperitoneal administration and also significantly lowered the glucose level of KK-Ay mice under similar conditions. Compounds 3 and 4, as well as senegose A (5), an oligosaccharide ester, were inactive when tested against normal mice.Entities:
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Year: 1997 PMID： 9214731 DOI： 10.1021/np9605403
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050