Literature DB >> 9210372

Cytokines: shared receptors, distinct functions.

J P DiSanto1.   

Abstract

That the signal transduction pathways used by the cytokines IL-2 and IL-15 are identical would suggest that these cytokines have redundant roles in lymphoid development; instead, IL-2 is the guardian of thymus-derived T-cell homeostasis, while interleukin-15 promotes extrathymic development of T and NK cells.

Entities:  

Mesh：

Substances：

Year:  1997        PMID： 9210372     DOI： 10.1016/s0960-9822(06)00208-9

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  16 in total

1.  Effector differentiation is not prerequisite for generation of memory cytotoxic T lymphocytes.

Authors:  N Manjunath; P Shankar; J Wan; W Weninger; M A Crowley; K Hieshima; T A Springer; X Fan; H Shen; J Lieberman; U H von Andrian
Journal:  J Clin Invest       Date:  2001-09       Impact factor: 14.808

2.  Detection of channel proximity by nanoparticle-assisted delaying of toxin binding; a combined patch-clamp and flow cytometric energy transfer study.

Authors:  Bálint Rubovszky; Péter Hajdú; Zoltán Krasznai; Rezsõ Gáspár; Thomas A Waldmann; Sándor Damjanovich; László Bene
Journal:  Eur Biophys J       Date:  2005-03       Impact factor: 1.733

3.  Celastrol suppresses the proliferation of lung adenocarcinoma cells by regulating microRNA-24 and microRNA-181b.

Authors:  Yun-Fei Yan; Han-Han Zhang; Qing Lv; Yue-Mei Liu; You-Jie Li; Bao-Sheng Li; Ping-Yu Wang; Wen-Jing Shang; Zhen Yue; Shu-Yang Xie
Journal:  Oncol Lett       Date:  2017-12-12       Impact factor: 2.967

Review 4.  Functions of IL-15 in anti-viral immunity: multiplicity and variety.

Authors:  Katherine C Verbist; Kimberly D Klonowski
Journal:  Cytokine       Date:  2012-06-15       Impact factor: 3.861

5.  Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway.

Authors:  G Baldassarre; M Fedele; S Battista; A Vecchione; A J Klein-Szanto; M Santoro; T A Waldmann; N Azimi; C M Croce; A Fusco
Journal:  Proc Natl Acad Sci U S A       Date:  2001-06-26       Impact factor: 11.205

6.  Functional dissection of the cytoplasmic subregions of the IL-2 receptor betac chain in primary lymphocyte populations.

Authors:  H Fujii; K Ogasawara; H Otsuka; M Suzuki; K Yamamura; T Yokochi; T Miyazaki; H Suzuki; T W Mak; S Taki; T Taniguchi
Journal:  EMBO J       Date:  1998-11-16       Impact factor: 11.598

7.  IL-2 therapy promotes suppressive ICOS+ Treg expansion in melanoma patients.

Authors:  Geok Choo Sim; Natalia Martin-Orozco; Lei Jin; Yan Yang; Sheng Wu; Edwina Washington; Deborah Sanders; Carol Lacey; Yijun Wang; Luis Vence; Patrick Hwu; Laszlo Radvanyi
Journal:  J Clin Invest       Date:  2014-01       Impact factor: 14.808

8.  T cell-independent interleukin 15Ralpha signals are required for bystander proliferation.

Authors:  J P Lodolce; P R Burkett; D L Boone; M Chien; A Ma
Journal:  J Exp Med       Date:  2001-10-15       Impact factor: 14.307

9.  The common cytokine receptor gamma chain and the pre-T cell receptor provide independent but critically overlapping signals in early alpha/beta T cell development.

Authors:  J P Di Santo; I Aifantis; E Rosmaraki; C Garcia; J Feinberg; H J Fehling; A Fischer; H von Boehmer; B Rocha
Journal:  J Exp Med       Date:  1999-02-01       Impact factor: 14.307

10.  In vivo survival and homeostatic proliferation of natural killer cells.

Authors:  Martin Prlic; Bruce R Blazar; Michael A Farrar; Stephen C Jameson
Journal:  J Exp Med       Date:  2003-04-14       Impact factor: 14.307
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.