Literature DB >> 9210368

Carcinogenesis: a balance between beta-catenin and APC.

B M Gumbiner1.   

Abstract

A protein first identified by its association with cadherin cell adhesion molecules, beta-catenin, has been implicated in carcinogenesis. In a number of different types of cancer, signalling through beta-catenin is upregulated either by direct mutation of beta-catenin or loss of negative regulation by the APC tumor suppressor protein.

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Year:  1997        PMID： 9210368     DOI： 10.1016/s0960-9822(06)00214-4

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  40 in total

1.  beta-catenin can be transported into the nucleus in a Ran-unassisted manner.

Authors:  F Yokoya; N Imamoto; T Tachibana; Y Yoneda
Journal:  Mol Biol Cell       Date:  1999-04       Impact factor: 4.138

2.  The p120(ctn)-binding partner Kaiso is a bi-modal DNA-binding protein that recognizes both a sequence-specific consensus and methylated CpG dinucleotides.

Authors:  Juliet M Daniel; Christopher M Spring; Howard C Crawford; Albert B Reynolds; Akeel Baig
Journal:  Nucleic Acids Res       Date:  2002-07-01       Impact factor: 16.971

3.  IQGAP1 protein regulates nuclear localization of β-catenin via importin-β5 protein in Wnt signaling.

Authors:  Toshiyasu Goto; Atsushi Sato; Shungo Adachi; Shun-ichiro Iemura; Tohru Natsume; Hiroshi Shibuya
Journal:  J Biol Chem       Date:  2013-11-06       Impact factor: 5.157

Review 4.  The angiogenic switch molecule, secreted FGF-binding protein, an indicator of early stages of pancreatic and colorectal adenocarcinoma.

Authors:  Elena Tassi; Anton Wellstein
Journal:  Semin Oncol       Date:  2006-12       Impact factor: 4.929

5.  The C-terminal cytoplasmic Lys-thr-X-X-X-Trp motif in frizzled receptors mediates Wnt/beta-catenin signalling.

Authors:  M Umbhauer; A Djiane; C Goisset; A Penzo-Méndez; J F Riou; J C Boucaut; D L Shi
Journal:  EMBO J       Date:  2000-09-15       Impact factor: 11.598

6.  Regulation of ribosomal S6 protein kinase-p90(rsk), glycogen synthase kinase 3, and beta-catenin in early Xenopus development.

Authors:  M A Torres; H Eldar-Finkelman; E G Krebs; R T Moon
Journal:  Mol Cell Biol       Date:  1999-02       Impact factor: 4.272

7.  N-cadherin redistribution during synaptogenesis in hippocampal neurons.

Authors:  D L Benson; H Tanaka
Journal:  J Neurosci       Date:  1998-09-01       Impact factor: 6.167

8.  Tumor angiogenesis: initiation and targeting - therapeutic targeting of an FGF-binding protein, an angiogenic switch molecule, and indicator of early stages of gastrointestinal adenocarcinomas -.

Authors:  Elena Tassi; Anton Wellstein
Journal:  Cancer Res Treat       Date:  2006-12-31       Impact factor: 4.679

9.  Expression of Dishevelled-1 in wound healing after acute myocardial infarction: possible involvement in myofibroblast proliferation and migration.

Authors:  Lijun Chen; Qingfeng Wu; Feng Guo; Beili Xia; Ji Zuo
Journal:  J Cell Mol Med       Date:  2004 Apr-Jun       Impact factor: 5.310

10.  Farnesoid X receptor deficiency in mice leads to increased intestinal epithelial cell proliferation and tumor development.

Authors:  Rengasamy R M Maran; Ann Thomas; Megan Roth; Zhonghua Sheng; Noriko Esterly; David Pinson; Xin Gao; Yawei Zhang; Vadivel Ganapathy; Frank J Gonzalez; Grace L Guo
Journal:  J Pharmacol Exp Ther       Date:  2008-11-03       Impact factor: 4.030
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