Literature DB >> 9204272

Recent solution structures of RNA and its complexes with drugs, peptides and proteins.

A Ramos1, C C Gubser, G Varani.   

Abstract

The past two years have seen remarkable progress in the study of RNA structure: the predicted era of RNA structural biology has arrived. Crystallographic structures of the hammerhead ribozyme and of a large subunit of a group I self-splicing intron have begun to reveal the structural basis of RNA enzymatic activity. A remarkable number of structures of small RNAs and of complexes with drugs, peptides and one protein domain have been determined by NMR.

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Year:  1997        PMID: 9204272     DOI: 10.1016/s0959-440x(97)80046-2

Source DB:  PubMed          Journal:  Curr Opin Struct Biol        ISSN: 0959-440X            Impact factor:   6.809


  11 in total

1.  Molecular dynamics simulations of the complex between human U1A protein and hairpin II of U1 small nuclear RNA and of free RNA in solution.

Authors:  Y Tang; L Nilsson
Journal:  Biophys J       Date:  1999-09       Impact factor: 4.033

Review 2.  Nucleic acid-based fluorescent probes and their analytical potential.

Authors:  Bernard Juskowiak
Journal:  Anal Bioanal Chem       Date:  2010-10-29       Impact factor: 4.142

3.  Simple, efficient protocol for enzymatic synthesis of uniformly 13C, 15N-labeled DNA for heteronuclear NMR studies.

Authors:  J E Masse; P Bortmann; T Dieckmann; J Feigon
Journal:  Nucleic Acids Res       Date:  1998-06-01       Impact factor: 16.971

4.  A two-metal ion mechanism operates in the hammerhead ribozyme-mediated cleavage of an RNA substrate.

Authors:  W B Lott; B W Pontius; P H von Hippel
Journal:  Proc Natl Acad Sci U S A       Date:  1998-01-20       Impact factor: 11.205

5.  A potential RNA drug target in the hepatitis C virus internal ribosomal entry site.

Authors:  R Klinck; E Westhof; S Walker; M Afshar; A Collier; F Aboul-Ela
Journal:  RNA       Date:  2000-10       Impact factor: 4.942

6.  A three-fluorophore FRET assay for high-throughput screening of small-molecule inhibitors of ribosome assembly.

Authors:  Dagmar Klostermeier; Pamela Sears; Chi-Huey Wong; David P Millar; James R Williamson
Journal:  Nucleic Acids Res       Date:  2004-05-17       Impact factor: 16.971

7.  Analysis of the conformation of the 3' major domain of Escherichia coli16S ribosomal RNA using site-directed photoaffinity crosslinking.

Authors:  A Montpetit; C Payant; J M Nolan; L Brakier-Gingras
Journal:  RNA       Date:  1998-11       Impact factor: 4.942

Review 8.  Regulation of mRNA transport, localization and translation in the nervous system of mammals (Review).

Authors:  Carlo Maria Di Liegro; Gabriella Schiera; Italia Di Liegro
Journal:  Int J Mol Med       Date:  2014-01-21       Impact factor: 4.101

9.  HIV-1 DIS stem loop forms an obligatory bent kissing intermediate in the dimerization pathway.

Authors:  Hansini Mundigala; Jonathan B Michaux; Andrew L Feig; Eric Ennifar; David Rueda
Journal:  Nucleic Acids Res       Date:  2014-05-09       Impact factor: 16.971

10.  Probing dynamics of HIV-1 nucleocapsid protein/target hexanucleotide complexes by 2-aminopurine.

Authors:  S V Avilov; E Piemont; V Shvadchak; H de Rocquigny; Y Mély
Journal:  Nucleic Acids Res       Date:  2007-12-17       Impact factor: 16.971

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