Literature DB >> 9204183

Yucatan pig: an optimal hairless model for a true random cutaneous flap.

L DeLuca, M Beckenstein, B Guyuron.   

Abstract

Porcine models have been used extensively for skin flap research because of the established similarity between the cutaneous blood supply of the swine and humans. The Yucatan minipig provides an excellent model for researching the properties of random cutaneous flaps, offering several advantages over other breeds of swine. In this study, a total of 67 random cutaneous dorsal flank flaps measuring 4 x 14 cm were raised on nine Yucatan minipigs. The mean survival length (10.03 +/- 1.60 cm) of the nondelayed flaps was greater than others reported in the literature. The well-defined plane between the subcutaneous tissue and the panniculus carnosus facilitated flap elevation consistently above the level of the panniculus carnosus thereby ensuring the creation of a true random cutaneous flap. Furthermore, the hairless nature of the skin, particularly beneficial in studying chemical peels, permits easy visualization and monitoring of any external skin changes. These advantages make the Yucatan minipig a more desirable alternative to other breeds of swine for use in skin flap research.

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Year:  1997        PMID: 9204183     DOI: 10.1007/s002669900111

Source DB:  PubMed          Journal:  Aesthetic Plast Surg        ISSN: 0364-216X            Impact factor:   2.326


  3 in total

1.  Early detection of complete vascular occlusion in a pedicle flap model using quantitative [corrected] spectral imaging.

Authors:  Michael R Pharaon; Thomas Scholz; Scott Bogdanoff; David Cuccia; Anthony J Durkin; David B Hoyt; Gregory R D Evans
Journal:  Plast Reconstr Surg       Date:  2010-12       Impact factor: 4.730

2.  Abnormalities of hair structure and skin histology derived from CRISPR/Cas9-based knockout of phospholipase C-delta 1 in mice.

Authors:  Yu-Min Liu; Wei Liu; Jun-Shuang Jia; Bang-Zhu Chen; Heng-Wei Chen; Yu Liu; Ya-Nan Bie; Peng Gu; Yan Sun; Dong Xiao; Wei-Wang Gu
Journal:  J Transl Med       Date:  2018-05-25       Impact factor: 5.531

3.  Generation of DKK1 transgenic Tibet minipigs by somatic cell nuclear transfer (SCNT).

Authors:  Wei Liu; Li-Hong Wu; Min Yue; Bayaer Nashun; Hua Tang; Yan Chen; Bang-Zhu Chen; Jin Yuan; Dong Xiao; Wei-Wang Gu
Journal:  Oncotarget       Date:  2017-09-01
  3 in total

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