Literature DB >> 9204011

Gene therapy: the case for cystic fibrosis.

E W Alton1, D Geddes.   

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Year:  1997        PMID: 9204011      PMCID: PMC1296098          DOI: 10.1177/014107689709031s09

Source DB:  PubMed          Journal:  J R Soc Med        ISSN: 0141-0768            Impact factor:   5.344


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  13 in total

1.  Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis.

Authors:  R G Crystal; N G McElvaney; M A Rosenfeld; C S Chu; A Mastrangeli; J G Hay; S L Brody; H A Jaffe; N T Eissa; C Danel
Journal:  Nat Genet       Date:  1994-09       Impact factor: 38.330

2.  Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA.

Authors:  J R Riordan; J M Rommens; B Kerem; N Alon; R Rozmahel; Z Grzelczak; J Zielenski; S Lok; N Plavsic; J L Chou
Journal:  Science       Date:  1989-09-08       Impact factor: 47.728

Review 3.  Abnormal regulation of ion channels in cystic fibrosis epithelia.

Authors:  M J Welsh
Journal:  FASEB J       Date:  1990-07       Impact factor: 5.191

4.  Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy.

Authors:  S C Hyde; D R Gill; C F Higgins; A E Trezise; L J MacVinish; A W Cuthbert; R Ratcliff; M J Evans; W H Colledge
Journal:  Nature       Date:  1993-03-18       Impact factor: 49.962

5.  Production of a severe cystic fibrosis mutation in mice by gene targeting.

Authors:  R Ratcliff; M J Evans; A W Cuthbert; L J MacVinish; D Foster; J R Anderson; W H Colledge
Journal:  Nat Genet       Date:  1993-05       Impact factor: 38.330

6.  Non-invasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice.

Authors:  E W Alton; P G Middleton; N J Caplen; S N Smith; D M Steel; F M Munkonge; P K Jeffery; D M Geddes; S L Hart; R Williamson
Journal:  Nat Genet       Date:  1993-10       Impact factor: 38.330

7.  Cystic fibrosis in the mouse by targeted insertional mutagenesis.

Authors:  J R Dorin; P Dickinson; E W Alton; S N Smith; D M Geddes; B J Stevenson; W L Kimber; S Fleming; A R Clarke; M L Hooper
Journal:  Nature       Date:  1992-09-17       Impact factor: 49.962

8.  Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis.

Authors:  J Zabner; L A Couture; R J Gregory; S M Graham; A E Smith; M J Welsh
Journal:  Cell       Date:  1993-10-22       Impact factor: 41.582

9.  A severe phenotype in mice with a duplication of exon 3 in the cystic fibrosis locus.

Authors:  W K O'Neal; P Hasty; P B McCray; B Casey; J Rivera-Pérez; M J Welsh; A L Beaudet; A Bradley
Journal:  Hum Mol Genet       Date:  1993-10       Impact factor: 6.150

10.  Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis.

Authors:  N J Caplen; E W Alton; P G Middleton; J R Dorin; B J Stevenson; X Gao; S R Durham; P K Jeffery; M E Hodson; C Coutelle
Journal:  Nat Med       Date:  1995-01       Impact factor: 53.440

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