Literature DB >> 92030

Differentiation of 3T3-L2 fibroblasts into adipose cells in bromodeoxyuridine-suppressed cultures.

T R Russell.   

Abstract

Growth of 3T3-L2 fibroblasts in medium containing 5-bromo-2'-deoxyuridine prevents the spontaneous cytodifferentiation of these cells into adipose cells. Treatment of bromodeoxyuridine-suppressed cultures at confluence with 1-methyl-3-isobutylxanthine, a promoter of the adipose conversion, results in differentiation of the fibroblasts into adipose cells but the extent of the conversion is less than that seen in cultures not treated with bromodeoxyuridine. 1-Methyl-3-isobutylxanthine appears to function without altering the amount of bromodeoxyuridine present in DNA.

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Year:  1979        PMID： 92030      PMCID： PMC411594          DOI： 10.1073/pnas.76.9.4451

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  20 in total

1.  Induction of lipogenesis during differentiation in a "preadipocyte" cell line.

Authors:  J C Mackall; A K Student; S E Polakis; M D Lane
Journal:  J Biol Chem       Date:  1976-10-25       Impact factor: 5.157

2.  An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion.

Authors:  H Green; O Kehinde
Journal:  Cell       Date:  1975-05       Impact factor: 41.582

3.  Acquisition of increased hormone sensitivity during in vitro adipocyte development.

Authors:  C S Rubin; E Lai; O M Rosen
Journal:  J Biol Chem       Date:  1977-05-25       Impact factor: 5.157

4.  Studies of lipoprotein lipase during the adipose conversion of 3T3 cells.

Authors:  L S Wise; H Green
Journal:  Cell       Date:  1978-02       Impact factor: 41.582

Review 5.  Toward molecular mechanisms of developmental processes.

Authors:  W J Rutter; R L Pictet; P W Morris
Journal:  Annu Rev Biochem       Date:  1973       Impact factor: 23.643

6.  Preferential inhibition by 5-bromodeoxyuridine of the synthesis of tyrosine aminotransferase in hepatoma cell cultures.

Authors:  R H Stellwagen; G M Tomkins
Journal:  J Mol Biol       Date:  1971-02-28       Impact factor: 5.469

7.  Deoxycytidine reverses the suppression of pigmentation caused by 5-BrdUrd without changing the amount of 5-BrdUrd in DNA.

Authors:  R L Davidson; E R Kaufman
Journal:  Cell       Date:  1977-12       Impact factor: 41.582

8.  Alterations in insulin binding accompanying differentiation of 3T3-L1 preadipocytes.

Authors:  B C Reed; S H Kaufmann; J C Mackall; A K Student; M D Lane
Journal:  Proc Natl Acad Sci U S A       Date:  1977-11       Impact factor: 11.205

9.  Conversion of 3T3 fibroblasts into adipose cells: triggering of differentiation by prostaglandin F2alpha and 1-methyl-3-isobutyl xanthine.

Authors:  T R Russell; R Ho
Journal:  Proc Natl Acad Sci U S A       Date:  1976-12       Impact factor: 11.205

10.  Selective interaction of 5'-bromodeoxyuridine substituted DNA with different chromosomal proteins.

Authors:  J S Gordon; G I Bell; H C Martinson; W J Rutter
Journal:  Biochemistry       Date:  1976-11-02       Impact factor: 3.162
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  2 in total

1.  Hydrogen sulfide promotes adipogenesis in 3T3L1 cells.

Authors:  Chin-Yi Tsai; Meng Teng Peh; Wei Feng; Brian William Dymock; Philip Keith Moore
Journal:  PLoS One       Date:  2015-03-30       Impact factor: 3.240

2.  Adipose cell differentiation in culture.

Authors:  G Ailhaud
Journal:  Mol Cell Biochem       Date:  1982-11-12       Impact factor: 3.396
  2 in total

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