Literature DB >> 9200541

Determination of acyclovir in human plasma by high-performance liquid chromatography.

R Boulieu1, C Gallant, N Silberstein.   

Abstract

A selective and sensitive isocratic high-performance liquid chromatographic method for the analysis of acyclovir in human plasma was described. Acid deproteinisation was used as sample treatment. Mean analytical recoveries were higher than 94% at low and high concentrations. The quantification limit was 0.1 mg/l for a plasma volume of 500 microl and precision study exhibits coefficients of variation lower than 5%. The method is suitable for therapeutic monitoring of acyclovir concentrations in organ-transplant recipients.

Entities:  

Mesh：

Substances：

Year:  1997        PMID： 9200541     DOI： 10.1016/s0378-4347(97)00037-6

Source DB:  PubMed          Journal:  J Chromatogr B Biomed Sci Appl        ISSN： 1387-2273


  3 in total

1.  Electronic estimations of renal function are inaccurate in solid-organ transplant recipients and can result in significant underdosing of prophylactic valganciclovir.

Authors:  J Trevillyan; P Angus; E Shelton; J Whitlam; F Ierino; J Pavlovic; D Gregory; K Urbancic; J Torresi; A Testro; M L Grayson
Journal:  Antimicrob Agents Chemother       Date:  2013-06-03       Impact factor: 5.191

2.  Design and development of multivesicular liposomal depot delivery system for controlled systemic delivery of acyclovir sodium.

Authors:  S K Jain; R K Jain; M K Chourasia; A K Jain; K B Chalasani; V Soni; A Jain
Journal:  AAPS PharmSciTech       Date:  2005-09-20       Impact factor: 3.246

3.  A newfangled study using risk silhouette and uncertainty approximation for quantification of acyclovir in diverse formulation.

Authors:  Karan Mittal; Riddhish Patadia; Chintan Vora; Rajashree C Mashru
Journal:  J Pharm Anal       Date:  2014-06-12
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.