| Literature DB >> 9200538 |
Y Takauchi1, H Kitagawa, T Kawada, T Akiyama, T Yamazaki.
Abstract
This study describes a high-performance liquid chromatographic method with electrochemical detection (HPLC-ED) for monitoring dihydroxyphenylglycol (DHPG) in the myocardial interstitial space. Using a cardiac dialysis technique, 10-microl dialysates were sampled from the myocardial interstitial space (1-min fractions) and were injected directly into the HPLC-ED system. The in vitro quantification limit for DHPG was 250 fg in a 10-microl injection. The basal DHPG concentration of dialysate was 181+/-46 pg/ml. This system offers a new possibility for monitoring myocardial interstitial DHPG levels.Entities:
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Year: 1997 PMID： 9200538 DOI： 10.1016/s0378-4347(97)00003-0
Source DB: PubMed Journal: J Chromatogr B Biomed Sci Appl ISSN： 1387-2273