Literature DB >> 9199478

Lymphocyte proliferative responses of goats vaccinated with Brucella melitensis 16M or a delta purE201 strain.

S C Olsen1, N F Cheville, M G Stevens, H H Houng, E S Drazek, T L Hadfield, R L Warren, D L Hoover.   

Abstract

The response to a Brucella melitensis purEK deletion mutant, delta purE201 (referred to as strain 201), was compared with the response to its parental strain, 16M, in juvenile goats. Proliferative responses to gamma-irradiated bacteria were detected earlier in strain 201-infected goats. Lymphocytes from strain 16M- or 201-infected goats proliferated in response to one-dimensional polyacrylamide gel electrophoresis-separated proteins of similar mass isolated from strain 16M or Brucella abortus RB51. Data from this study suggest that some antigens stimulating cell-mediated responses are conserved among Brucella species, as 201- and 16M-infected goats recognized similar proteins expressed by RB51 and 16M.

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Year:  1997        PMID： 9199478      PMCID： PMC175420          DOI： 10.1128/iai.65.7.2987-2991.1997

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  11 in total

1.  Bacterial persistence and immunity in goats vaccinated with a purE deletion mutant or the parental 16M strain of Brucella melitensis.

Authors:  N F Cheville; S C Olsen; A E Jensen; M G Stevens; A M Florance; H S Houng; E S Drazek; R L Warren; T L Hadfield; D L Hoover
Journal:  Infect Immun       Date:  1996-07       Impact factor: 3.441

2.  Macrophage activation during experimental murine brucellosis. II. Inhibition of in vitro lymphocyte proliferation by brucella-activated macrophages.

Authors:  C Riglar; C Cheers
Journal:  Cell Immunol       Date:  1980-01       Impact factor: 4.868

3.  Deletion of purE attenuates Brucella melitensis infection in mice.

Authors:  R M Crawford; L Van De Verg; L Yuan; T L Hadfield; R L Warren; E S Drazek; H H Houng; C Hammack; K Sasala; T Polsinelli; J Thompson; D L Hoover
Journal:  Infect Immun       Date:  1996-06       Impact factor: 3.441

4.  Deletion of purE attenuates Brucella melitensis 16M for growth in human monocyte-derived macrophages.

Authors:  E S Drazek; H S Houng; R M Crawford; T L Hadfield; D L Hoover; R L Warren
Journal:  Infect Immun       Date:  1995-09       Impact factor: 3.441

5.  Immune responses and protection against infection and abortion in cattle experimentally vaccinated with mutant strains of Brucella abortus.

Authors:  N F Cheville; M G Stevens; A E Jensen; F M Tatum; S M Halling
Journal:  Am J Vet Res       Date:  1993-10       Impact factor: 1.156

6.  Serologic responses in diagnostic tests for brucellosis in cattle vaccinated with Brucella abortus 19 or RB51.

Authors:  M G Stevens; S G Hennager; S C Olsen; N F Cheville
Journal:  J Clin Microbiol       Date:  1994-04       Impact factor: 5.948

7.  Vaccination with Brucella abortus rough mutant RB51 protects BALB/c mice against virulent strains of Brucella abortus, Brucella melitensis, and Brucella ovis.

Authors:  M P Jiménez de Bagüés; P H Elzer; S M Jones; J M Blasco; F M Enright; G G Schurig; A J Winter
Journal:  Infect Immun       Date:  1994-11       Impact factor: 3.441

8.  Reactions catalyzed by 5-aminoimidazole ribonucleotide carboxylases from Escherichia coli and Gallus gallus: a case for divergent catalytic mechanisms.

Authors:  S M Firestine; S W Poon; E J Mueller; J Stubbe; V J Davisson
Journal:  Biochemistry       Date:  1994-10-04       Impact factor: 3.162

9.  Comparative analysis of immune responses in cattle vaccinated with Brucella abortus strain 19 or strain RB51.

Authors:  M G Stevens; S C Olsen; N F Cheville
Journal:  Vet Immunol Immunopathol       Date:  1995-02       Impact factor: 2.046

10.  Lymphocyte proliferation in response to immunodominant antigens of Brucella abortus 2308 and RB51 in strain 2308-infected cattle.

Authors:  M G Stevens; S C Olsen; N F Cheville
Journal:  Infect Immun       Date:  1994-10       Impact factor: 3.441
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  3 in total

1.  Protection of mice against brucellosis by vaccination with Brucella melitensis WR201(16MDeltapurEK).

Authors:  D L Hoover; R M Crawford; L L Van De Verg; M J Izadjoo; A K Bhattacharjee; C M Paranavitana; R L Warren; M P Nikolich; T L Hadfield
Journal:  Infect Immun       Date:  1999-11       Impact factor: 3.441

Review 2.  Molecular host-pathogen interaction in brucellosis: current understanding and future approaches to vaccine development for mice and humans.

Authors:  Jinkyung Ko; Gary A Splitter
Journal:  Clin Microbiol Rev       Date:  2003-01       Impact factor: 26.132

3.  Evaluation of shedding, tissue burdens, and humoral immune response in goats after experimental challenge with the virulent Brucella melitensis strain 16M and the reduced virulence vaccine strain Rev. 1.

Authors:  Jennifer L Higgins; Mercedes Gonzalez-Juarrero; Richard A Bowen
Journal:  PLoS One       Date:  2017-10-13       Impact factor: 3.240
  3 in total

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