Literature DB >> 9199475

Role of gamma interferon in the pathogenesis of bacteremic pneumococcal pneumonia.

J B Rubins1, C Pomeroy.   

Abstract

Gamma interferon (IFN-gamma) concentrations in blood, but not in lungs, rose significantly at 24 to 48 h after murine pulmonary infection with virulent pneumococci. In contrast, infection with avirulent pneumococcal strains produced minimal rises in serum IFN-gamma concentrations. Compared with that of immunocompetent mice, mortality was appreciably increased after pulmonary infection of IFN-gamma gene knockout mice, suggesting a protective role for IFN-gamma in host response to pneumococcal disease.

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Year:  1997        PMID： 9199475      PMCID： PMC175417          DOI： 10.1128/iai.65.7.2975-2977.1997

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  21 in total

1.  Role of interferon in streptococcal infection in the mouse.

Authors:  D A Weigent; T L Huff; J W Peterson; G J Stanton; S Baron
Journal:  Microb Pathog       Date:  1986-08       Impact factor: 3.738

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Authors:  T van der Poll; A Marchant; C V Keogh; M Goldman; S F Lowry
Journal:  J Infect Dis       Date:  1996-11       Impact factor: 5.226

3.  Failure of intensive care unit support to influence mortality from pneumococcal bacteremia.

Authors:  E W Hook; C A Horton; D R Schaberg
Journal:  JAMA       Date:  1983-02-25       Impact factor: 56.272

4.  Impaired production of lymphokines and immune (gamma) interferon in the acquired immunodeficiency syndrome.

Authors:  H W Murray; B Y Rubin; H Masur; R B Roberts
Journal:  N Engl J Med       Date:  1984-04-05       Impact factor: 91.245

5.  Evaluation of T lymphocyte effector function in immunodeficiency diseases: abnormality in mitogen-stimulated interferon in patients with selective IgA deficiency.

Authors:  L B Epstein; A J Ammann
Journal:  J Immunol       Date:  1974-02       Impact factor: 5.422

6.  Role of interferon-gamma in experimental gram-negative sepsis.

Authors:  A T Silva; J Cohen
Journal:  J Infect Dis       Date:  1992-08       Impact factor: 5.226

Review 7.  Antimicrobial resistance in Streptococcus pneumoniae: an overview.

Authors:  P C Appelbaum
Journal:  Clin Infect Dis       Date:  1992-07       Impact factor: 9.079

8.  Interferon production in primary immunodeficiencies.

Authors:  P M Matricardi; M R Capobianchi; R Paganelli; J Facchini; M C Sirianni; R Seminara; F Dianzani; F Aiuti
Journal:  J Clin Immunol       Date:  1984-09       Impact factor: 8.317

9.  Pneumococcal bacteremia--no change in mortality in 30 years: analysis of 104 cases and review of the literature.

Authors:  M R Kramer; B Rudensky; I Hadas-Halperin; M Isacsohn; E Melzer
Journal:  Isr J Med Sci       Date:  1987-03

Review 10.  Interferon-gamma, the activated macrophage, and host defense against microbial challenge.

Authors:  H W Murray
Journal:  Ann Intern Med       Date:  1988-04       Impact factor: 25.391
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  46 in total

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3.  Differential PsaA-, PspA-, PspC-, and PdB-specific immune responses in a mouse model of pneumococcal carriage.

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4.  Pneumococcal capsular polysaccharide vaccine-mediated protection against serotype 3 Streptococcus pneumoniae in immunodeficient mice.

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Journal:  Infect Immun       Date:  2007-01-12       Impact factor: 3.441

5.  Intranasal vaccination with chitosan-DNA nanoparticles expressing pneumococcal surface antigen a protects mice against nasopharyngeal colonization by Streptococcus pneumoniae.

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Journal:  Clin Vaccine Immunol       Date:  2010-11-03

6.  Interferon-inducible protein 10, but not monokine induced by gamma interferon, promotes protective type 1 immunity in murine Klebsiella pneumoniae pneumonia.

Authors:  Xianying Zeng; Thomas A Moore; Michael W Newstead; Jane C Deng; Steven L Kunkel; Andrew D Luster; Theodore J Standiford
Journal:  Infect Immun       Date:  2005-12       Impact factor: 3.441

Review 7.  Murine Models of Sepsis and Trauma: Can We Bridge the Gap?

Authors:  Julie A Stortz; Steven L Raymond; Juan C Mira; Lyle L Moldawer; Alicia M Mohr; Philip A Efron
Journal:  ILAR J       Date:  2017-07-01

8.  Interleukin-12 promotes gamma interferon-dependent neutrophil recruitment in the lung and improves protection against respiratory Streptococcus pneumoniae infection.

Authors:  Keer Sun; Sharon L Salmon; Steven A Lotz; Dennis W Metzger
Journal:  Infect Immun       Date:  2007-01-08       Impact factor: 3.441

9.  Helper T cell epitope-mapping reveals MHC-peptide binding affinities that correlate with T helper cell responses to pneumococcal surface protein A.

Authors:  Rajesh Singh; Shailesh Singh; Praveen K Sharma; Udai P Singh; David E Briles; Susan K Hollingshead; James W Lillard
Journal:  PLoS One       Date:  2010-02-25       Impact factor: 3.240

10.  STAT4 is a critical mediator of early innate immune responses against pulmonary Klebsiella infection.

Authors:  Jane C Deng; Xianying Zeng; Michael Newstead; Thomas A Moore; Wan C Tsai; Victor J Thannickal; Theodore J Standiford
Journal:  J Immunol       Date:  2004-09-15       Impact factor: 5.422
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