Literature DB >> 9198177

Protein C deficiency: from gene defects to disease.

P H Reitsma1.   

Abstract

Genetic defects in the protein C pathway are associated with an increased risk for venous thrombosis. This review will focus on the nature of the defects in the protein C gene that underlie protein C deficiency and the relationship with thrombotic disease.

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Year:  1997        PMID： 9198177

Source DB:  PubMed          Journal:  Thromb Haemost        ISSN： 0340-6245            Impact factor:   5.249


  8 in total

Review 1.  Candidate genes and confirmed genetic polymorphisms associated with cardiovascular diseases: a tabular assessment.

Authors:  Z Tang; R P Tracy
Journal:  J Thromb Thrombolysis       Date:  2001-02       Impact factor: 2.300

2.  Modeling zymogen protein C.

Authors:  L Perera; C Foley; T A Darden; D Stafford; T Mather; C T Esmon; L G Pedersen
Journal:  Biophys J       Date:  2000-12       Impact factor: 4.033

3.  Expression and functional characterisation of natural R147W and K150del variants of protein C in the Chinese population.

Authors:  Qiulan Ding; Likui Yang; Seyed Mahdi Hassanian; A R Rezaie
Journal:  Thromb Haemost       Date:  2013-02-07       Impact factor: 5.249

Review 4.  Empirical and theoretical phenotypic discrimination.

Authors:  K E Brummel-Ziedins; T Orfeo; F R Rosendaal; A Undas; G E Rivard; S Butenas; K G Mann
Journal:  J Thromb Haemost       Date:  2009-07       Impact factor: 5.824

5.  Using a Systems Pharmacology Model of the Blood Coagulation Network to Predict the Effects of Various Therapies on Biomarkers.

Authors:  S Nayak; D Lee; S Patel-Hett; D D Pittman; S W Martin; A C Heatherington; P Vicini; F Hua
Journal:  CPT Pharmacometrics Syst Pharmacol       Date:  2015-06-19

6.  Severe congenital protein C deficiency: the use of protein C concentrates (human) as replacement therapy for life-threatening blood-clotting complications.

Authors:  Paul N Knoebl
Journal:  Biologics       Date:  2008-06

7.  In silico thrombin generation: Plasma composition imbalance and mortality in human immunodeficiency virus.

Authors:  Kathleen E Brummel-Ziedins; Matthew Gissel; Jacqueline Neuhaus; Álvaro H Borges; David R Chadwick; Sean Emery; James D Neaton; Russell P Tracy; Jason V Baker
Journal:  Res Pract Thromb Haemost       Date:  2018-09-11

8.  Comparison of clot-based and chromogenic assay for the determination of protein c activity.

Authors:  Tariq M Roshan; Nancy Stein; Xiu Y Jiang
Journal:  Blood Coagul Fibrinolysis       Date:  2019-06       Impact factor: 1.276
  8 in total

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