Literature DB >> 919693

Promotion of leishmanial infections in non-permissive host macrophages by conditioned medium.

E Handman, C L Greenblatt.   

Abstract

Leishmania enriettii grows well in guinea pig macrophages in culture but fails to do so in mouse macrophages. Dialyzed and concentrated conditioned medium from L. enriettii cultures promoted the infection in the mouse macrophages at 37 degrees C and at 32 degrees C. Similarly processed medium on which L. tropica had been cultured did not cause the same effect. Immune precipitation of the conditioned medium by anti-Leishmania serum cancelled out the effect. Infections of guinea pig macrophages by L. tropica were also enhanced by the homologous medium, but we were unable to quantitate the effect.

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Year:  1977        PMID： 919693     DOI： 10.1007/bf00380458

Source DB:  PubMed          Journal:  Z Parasitenkd        ISSN： 0044-3255


  11 in total

1.  THE FINE STRUCTURE OF LEISHMANIA DONOVANI AND THE ROLE OF THE KINETOPLAST IN THE LEISHMANI-LEPTOMONAD TRANSFORMATION.

Authors:  M A RUDZINSKA; P A D ALESANDRO; W TRAGER
Journal:  J Protozool       Date:  1964-05

2.  TEMPERATURE EFFECT ON LEISHMANIA ENRIETTII IN VITRO.

Authors:  C L GREENBLATT; P GLASER
Journal:  Exp Parasitol       Date:  1965-02       Impact factor: 2.011

3.  Fusion of host cell secondary lysosomes with the parasitophorous vacuoles of Leishmania mexicana-infected macrophages.

Authors:  J Alexander; K Vickerman
Journal:  J Protozool       Date:  1975-11

4.  Macrophages and intracellular parasitism.

Authors:  T C Jones
Journal:  J Reticuloendothel Soc       Date:  1974-05

5.  Leishmanial serotypes as distinguished by the gel diffusion of factors excreted in vitro and in vivo.

Authors:  L F Schnur; A Zuckerman; C L Greenblatt
Journal:  Isr J Med Sci       Date:  1972-07

6.  The effect of homologous rabbit antiserum on the growth of Leishmania tarentolae--a fine structure study.

Authors:  P R Strauss
Journal:  J Protozool       Date:  1971-02

7.  Electron-transparent zone of mycobacteria may be a defence mechanism.

Authors:  P Draper; R J Rees
Journal:  Nature       Date:  1970-11-28       Impact factor: 49.962

8.  Response of cultured macrophages to Mycobacterium tuberculosis, with observations on fusion of lysosomes with phagosomes.

Authors:  J A Armstrong; P D Hart
Journal:  J Exp Med       Date:  1971-09-01       Impact factor: 14.307

9.  Antibody-induced movement of membrane components of Leishmania enriettii.

Authors:  J J Doyle; R Behin; J Mauel; D S Rowe
Journal:  J Exp Med       Date:  1974-05-01       Impact factor: 14.307

10.  The interaction between Toxoplasma gondii and mammalian cells. II. The absence of lysosomal fusion with phagocytic vacuoles containing living parasites.

Authors:  T C Jones; J G Hirsch
Journal:  J Exp Med       Date:  1972-11-01       Impact factor: 14.307
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  7 in total

1.  Interactions between murine macrophages and obligate intracellular protozoa.

Authors:  T C Jones
Journal:  Am J Pathol       Date:  1981-01       Impact factor: 4.307

2.  Solubilization and partial purification of a cell surface component of Leishmania braziliensis.

Authors:  J A Misle; M E Márquez; A G Hernández
Journal:  Z Parasitenkd       Date:  1985

3.  Cell surface origin of antigens shed by Leishmania donovani during growth in axenic culture.

Authors:  E S Kaneshiro; M Gottlieb; D M Dwyer
Journal:  Infect Immun       Date:  1982-08       Impact factor: 3.441

4.  Leishmanial excreted factor: protein-bound and free forms from promastigote cultures of Leishmania tropica and Leishmania donovani.

Authors:  G M Slutzky; J El-On; C L Greenblatt
Journal:  Infect Immun       Date:  1979-12       Impact factor: 3.441

5.  Identification of galactose as the immunodominant sugar of leishmanial excreted factor and subsequent labeling with galactose oxidase and sodium boro[3H]hydride.

Authors:  G M Slutzky; C L Greenblatt
Journal:  Infect Immun       Date:  1982-07       Impact factor: 3.441

6.  Phenotypic diversity of cloned lines of Leishmania major promastigotes.

Authors:  C L Greenblatt; E Handman; G F Mitchell; F L Battye; L F Schnur; D Snary
Journal:  Z Parasitenkd       Date:  1985

7.  An amphipathic sulphated glycoconjugate of Leishmania: characterization with monoclonal antibodies.

Authors:  E Handman; C L Greenblatt; J W Goding
Journal:  EMBO J       Date:  1984-10       Impact factor: 11.598
  7 in total

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