| Literature DB >> 9195699 |
A Crossley1, J E Calvert, P R Taylor, A M Dickinson.
Abstract
In this study we have compared two assays for the detection of autoantibodies GpIIb/IIIa, platelet bound and in serum, in immune thrombocytopenic purpura (ITP). Both assays were found to have a similar sensitivity, but the monoclonal antibody immobilization of platelet antigen (MAIPA) assay was more reproducible than the immunobead assay. The MAIPA and immunobead assay demonstrated an 81% concordance of results for serum antibody detection and a 78% concordance for platelet-associated antibody detection, with an 8-12% incidence of false positive or negative results.Entities:
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Year: 1997 PMID： 9195699 DOI： 10.1046/j.1365-3148.1997.d01-15.x
Source DB: PubMed Journal: Transfus Med ISSN： 0958-7578 Impact factor: 2.019