Literature DB >> 9195221

Phase I study of direct administration of a replication deficient adenovirus vector containing the E. coli cytosine deaminase gene to metastatic colon carcinoma of the liver in association with the oral administration of the pro-drug 5-fluorocytosine.

R G Crystal1, E Hirschowitz, M Lieberman, J Daly, E Kazam, C Henschke, D Yankelevitz, N Kemeny, R Silverstein, A Ohwada, T Russi, A Mastrangeli, A Sanders, J Cooke, B G Harvey.   

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Year:  1997        PMID： 9195221     DOI： 10.1089/hum.1997.8.8-985

Source DB:  PubMed          Journal:  Hum Gene Ther        ISSN： 1043-0342            Impact factor:   5.695


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  24 in total

1.  Functional analysis of adenovirus protein IX identifies domains involved in capsid stability, transcriptional activity, and nuclear reorganization.

Authors:  M Rosa-Calatrava; L Grave; F Puvion-Dutilleul; B Chatton; C Kedinger
Journal:  J Virol       Date:  2001-08       Impact factor: 5.103

2.  A protein therapeutic modality founded on molecular regulation.

Authors:  Chapman M Wright; R Clay Wright; James R Eshleman; Marc Ostermeier
Journal:  Proc Natl Acad Sci U S A       Date:  2011-09-19       Impact factor: 11.205

3.  Noninvasive quantitation of cytosine deaminase transgene expression in human tumor xenografts with in vivo magnetic resonance spectroscopy.

Authors:  L D Stegman; A Rehemtulla; B Beattie; E Kievit; T S Lawrence; R G Blasberg; J G Tjuvajev; B D Ross
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-17       Impact factor: 11.205

Review 4.  Angiogenesis gene therapy to rescue ischaemic tissues: achievements and future directions.

Authors:  C Emanueli; P Madeddu
Journal:  Br J Pharmacol       Date:  2001-08       Impact factor: 8.739

5.  Variability of human systemic humoral immune responses to adenovirus gene transfer vectors administered to different organs.

Authors:  B G Harvey; N R Hackett; T El-Sawy; T K Rosengart; E A Hirschowitz; M D Lieberman; M L Lesser; R G Crystal
Journal:  J Virol       Date:  1999-08       Impact factor: 5.103

6.  Transcriptional control of viral gene therapy by cisplatin.

Authors:  James O Park; Carlos A Lopez; Vinay K Gupta; Charles K Brown; Helena J Mauceri; Thomas E Darga; Abdullah Manan; Samuel Hellman; Mitchell C Posner; Donald W Kufe; Ralph R Weichselbaum
Journal:  J Clin Invest       Date:  2002-08       Impact factor: 14.808

7.  Non-invasive molecular and functional imaging of cytosine deaminase and uracil phosphoribosyltransferase fused with red fluorescence protein.

Authors:  Ligang Xing; Xuelong Deng; Khushali Kotedia; Ellen Ackerstaff; Vladimir Ponomarev; C Clifton Ling; Jason A Koutcher; Gloria C Li
Journal:  Acta Oncol       Date:  2008       Impact factor: 4.089

8.  Efficient expression of CFTR function with adeno-associated virus vectors that carry shortened CFTR genes.

Authors:  L Zhang; D Wang; H Fischer; P D Fan; J H Widdicombe; Y W Kan; J Y Dong
Journal:  Proc Natl Acad Sci U S A       Date:  1998-08-18       Impact factor: 11.205

9.  Suppression of the growth of human colorectal cancer cells by therapeutic stem cells expressing cytosine deaminase and interferon-β via their tumor-tropic effect in cellular and xenograft mouse models.

Authors:  Bo-Rim Yi; Min-Ah Park; Hye-Rim Lee; Nam-Hee Kang; Kelvin J Choi; Seung U Kim; Kyung-Chul Choi
Journal:  Mol Oncol       Date:  2013-01-19       Impact factor: 6.603

Review 10.  Gene therapy for gastric cancer: a review.

Authors:  Chao Zhang; Zhan-Kui Liu
Journal:  World J Gastroenterol       Date:  2003-11       Impact factor: 5.742
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