| Literature DB >> 9194682 |
P Fischer1, M E Götz, W Danielczyk, W Gsell, P Riederer.
Abstract
In the present study we found a significant correlation between severity of dementia of Alzheimer's type (DAT) and both transferrin and ferritin serum levels. Levels of transferrin in serum of 41 DAT patients tended to be lower than those of 19 age-matched controls, while levels of ferritin were not significantly different in DAT patients compared to controls. These results are interpreted in line with previous findings of higher brain ferritin and lower brain transferrin levels in DAT and are a circumstantial support for the oxygen radical hypothesis of degenerative brain disease.Entities:
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Year: 1997 PMID: 9194682 DOI: 10.1016/s0024-3205(97)00282-8
Source DB: PubMed Journal: Life Sci ISSN: 0024-3205 Impact factor: 5.037