Literature DB >> 9194682

Blood transferrin and ferritin in Alzheimer's disease.

P Fischer1, M E Götz, W Danielczyk, W Gsell, P Riederer.   

Abstract

In the present study we found a significant correlation between severity of dementia of Alzheimer's type (DAT) and both transferrin and ferritin serum levels. Levels of transferrin in serum of 41 DAT patients tended to be lower than those of 19 age-matched controls, while levels of ferritin were not significantly different in DAT patients compared to controls. These results are interpreted in line with previous findings of higher brain ferritin and lower brain transferrin levels in DAT and are a circumstantial support for the oxygen radical hypothesis of degenerative brain disease.

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Year:  1997        PMID: 9194682     DOI: 10.1016/s0024-3205(97)00282-8

Source DB:  PubMed          Journal:  Life Sci        ISSN: 0024-3205            Impact factor:   5.037


  11 in total

1.  Selective translational control of the Alzheimer amyloid precursor protein transcript by iron regulatory protein-1.

Authors:  Hyun-Hee Cho; Catherine M Cahill; Charles R Vanderburg; Clemens R Scherzer; Bin Wang; Xudong Huang; Jack T Rogers
Journal:  J Biol Chem       Date:  2010-06-17       Impact factor: 5.157

2.  Detection, identification and mapping of iron anomalies in brain tissue using X-ray absorption spectroscopy.

Authors:  A Mikhaylova; M Davidson; H Toastmann; J E T Channell; Y Guyodo; C Batich; J Dobson
Journal:  J R Soc Interface       Date:  2005-03-22       Impact factor: 4.118

Review 3.  Alteration of Iron Concentration in Alzheimer's Disease as a Possible Diagnostic Biomarker Unveiling Ferroptosis.

Authors:  Eleonora Ficiarà; Zunaira Munir; Silvia Boschi; Maria Eugenia Caligiuri; Caterina Guiot
Journal:  Int J Mol Sci       Date:  2021-04-25       Impact factor: 5.923

4.  Ceruloplasmin and iron proteins in the serum of patients with Alzheimer's disease.

Authors:  Gudlaug Torsdottir; Jakob Kristinsson; Jón Snaedal; Torkell Jóhannesson
Journal:  Dement Geriatr Cogn Dis Extra       Date:  2011-11-05

5.  Multivariate protein signatures of pre-clinical Alzheimer's disease in the Alzheimer's disease neuroimaging initiative (ADNI) plasma proteome dataset.

Authors:  Daniel Johnstone; Elizabeth A Milward; Regina Berretta; Pablo Moscato
Journal:  PLoS One       Date:  2012-04-02       Impact factor: 3.240

6.  Proteomic Profiling of Plasma and Brain Tissue from Alzheimer's Disease Patients Reveals Candidate Network of Plasma Biomarkers.

Authors:  Mei Chen; Weiming Xia
Journal:  J Alzheimers Dis       Date:  2020       Impact factor: 4.160

7.  Plasma protein biomarker model for screening Alzheimer disease using multiple reaction monitoring-mass spectrometry.

Authors:  Yeongshin Kim; Jaenyeon Kim; Minsoo Son; Jihyeon Lee; Injoon Yeo; Kyu Yeong Choi; Hoowon Kim; Byeong C Kim; Kun Ho Lee; Youngsoo Kim
Journal:  Sci Rep       Date:  2022-01-24       Impact factor: 4.379

8.  Serum ferritin and metal levels as risk factors for amyotrophic lateral sclerosis.

Authors:  Muddasir Qureshi; Robert H Brown; Jack T Rogers; Merit E Cudkowicz
Journal:  Open Neurol J       Date:  2008-09-12

9.  Transferrin is responsible for mediating the effects of iron ions on the regulation of anterior pharynx-defective-1α/β and Presenilin 1 expression via PGE2 and PGD2 at the early stage of Alzheimer's Disease.

Authors:  Chen-Di Lu; Ji-Kang Ma; Zheng-Yang Luo; Qun-Xi Tai; Pu Wang; Pei-Pei Guan
Journal:  Aging (Albany NY)       Date:  2018-11-01       Impact factor: 5.682

10.  Association of Plasma Transferrin With Cognitive Decline in Patients With Mild Cognitive Impairment and Alzheimer's Disease.

Authors:  Jingjing Guan; Peng Wang; Liping Lu; Guanan Zhao
Journal:  Front Aging Neurosci       Date:  2020-03-12       Impact factor: 5.750

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