Literature DB >> 9194558

Double identity for proteins of the Bcl-2 family.

J C Reed1.   

Abstract

Bcl-2 is an oncogenic protein that acts by inhibiting programmed cell death. The mechanisms used by this and related anti-apoptotic proteins to protect cells from cytotoxic stimuli are now emerging, with the discovery that Bcl-2 can function both as an ion channel and as an adaptor or docking protein.

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Year:  1997        PMID： 9194558     DOI： 10.1038/42867

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  254 in total

1.  Enhanced B cell survival in familial macroglobulinaemia is associated with increased expression of Bcl-2.

Authors:  H M Ogmundsdóttir; S Sveinsdóttir; A Sigfússon; I Skaftadóttir; J G Jónasson; B A Agnarsson
Journal:  Clin Exp Immunol       Date:  1999-08       Impact factor: 4.330

2.  Paracrine control of endothelial cell survival.

Authors:  D C Altieri
Journal:  J Clin Invest       Date:  1999-10       Impact factor: 14.808

Review 3.  Antisense cancer therapy: the state of the science.

Authors:  D M Kushner; R H Silverman
Journal:  Curr Oncol Rep       Date:  2000-01       Impact factor: 5.075

4.  NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis.

Authors:  C Y Wang; D C Guttridge; M W Mayo; A S Baldwin
Journal:  Mol Cell Biol       Date:  1999-09       Impact factor: 4.272

5.  Bcl-2 is a monomeric protein: prevention of homodimerization by structural constraints.

Authors:  S Conus; T Kaufmann; I Fellay; I Otter; T Rossé; C Borner
Journal:  EMBO J       Date:  2000-04-03       Impact factor: 11.598

Review 6.  Mitochondria and apoptosis: HQ or high-security prison?

Authors:  N J Waterhouse; D R Green
Journal:  J Clin Immunol       Date:  1999-11       Impact factor: 8.317

7.  Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria.

Authors:  B Antonsson; S Montessuit; S Lauper; R Eskes; J C Martinou
Journal:  Biochem J       Date:  2000-01-15       Impact factor: 3.857

8.  Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane.

Authors:  R Eskes; S Desagher; B Antonsson; J C Martinou
Journal:  Mol Cell Biol       Date:  2000-02       Impact factor: 4.272

9.  Role of Nr13 in regulation of programmed cell death in the bursa of Fabricius.

Authors:  R M Lee; G Gillet; J Burnside; S J Thomas; P Neiman
Journal:  Genes Dev       Date:  1999-03-15       Impact factor: 11.361

10.  Activation of membrane-associated procaspase-3 is regulated by Bcl-2.

Authors:  J F Krebs; R C Armstrong; A Srinivasan; T Aja; A M Wong; A Aboy; R Sayers; B Pham; T Vu; K Hoang; D S Karanewsky; C Leist; A Schmitz; J C Wu; K J Tomaselli; L C Fritz
Journal:  J Cell Biol       Date:  1999-03-08       Impact factor: 10.539
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