Literature DB >> 9194065

Organization of the Drosophila genome in mutants with changes in second messenger metabolism and learning ability.

A V Medvedeva1, E V Tokmacheva, E V Savvateeva, V S Kornitskii.   

Abstract

Mechanisms modifying the structural-functional organization of polytene chromosomes were studied in a Drosophila line in which the activating properties of calmodulin were altered and learning ability was increased, by treating mutants with homeopathic preparations which affect Ca2+ and F- ion metabolism. The results indicated a dominant role for Ca2+ ions and calmodulin in determining the chromocentric organization of the nucleus. F- ions, which stimulate the adenylate cyclase complex, were found not to have a role.

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Year:  1997        PMID: 9194065     DOI: 10.1007/BF02462893

Source DB:  PubMed          Journal:  Neurosci Behav Physiol        ISSN: 0097-0549


  4 in total

1.  Allelic pairing and gene regulation: A model for the zeste-white interaction in Drosophila melanogaster.

Authors:  J W Jack; B H Judd
Journal:  Proc Natl Acad Sci U S A       Date:  1979-03       Impact factor: 11.205

2.  [The effect of temperature on the 3-dimensional organization of polytene chromosomes in Drosophila mutants with altered calmodulin functions].

Authors:  A V Medvedeva; E V Savvateeva
Journal:  Dokl Akad Nauk SSSR       Date:  1991

3.  [The effect of ts mutations in the agnostic gene controlling calmodulin functions and learning capacity on the ectopic conjugation of polytene chromosomes in Drosophila].

Authors:  A V Medvedeva; E V Savvateeva
Journal:  Dokl Akad Nauk SSSR       Date:  1991

4.  [Ectopic interactions of Drosophila melanogaster polytene chromosomes in the H-E system of hybrid dysgenesis].

Authors:  N I Ivashchenko; R B Vagapova; Iu F Bogdanov
Journal:  Genetika       Date:  1991-12
  4 in total

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