Scirrhous eosinophilic gastritis in dogs with gastric arteritis.

Three adult spayed female hunting dogs had an unusual form of chronic active gastritis. The disease lasted for months to several years. Vomiting was the most consistent clinical sign. One dog had leukocytosis with 30 percent eosinophils. The stomach of each dog was enlarged and greatly thickened. Collagen deposits, granulation tissue and eosinophils replaced most of the gastric wall. Disease of the gastric arteries ranged from fibrinoid necrosis to panarteritis. Granulation tissue obstructed the omental arteries of one dog. There also was splenic reticuloendothelial hyperplasia with fibrosis, hemorrhage and congestion, and chronic eosinophilic lymphadenitis. Although the cause of this disease was not determined, its basis probably was immunologic.