Literature DB >> 9191972

Toward a novel metal-based chemotherapy against tropical diseases. 3. Synthesis and antimalarial activity in vitro and in vivo of the new gold-chloroquine complex [Au(PPh3)(CQ)]PF6.

M Navarro1, H Pérez, R A Sánchez-Delgado.   

Abstract

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Year:  1997        PMID： 9191972     DOI： 10.1021/jm9607358

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  19 in total

1.  Synthesis and antimalarial activity of metal complexes of cross-bridged tetraazamacrocyclic ligands.

Authors:  Timothy J Hubin; Prince N-A Amoyaw; Kimberly D Roewe; Natalie C Simpson; Randall D Maples; TaRynn N Carder Freeman; Amy N Cain; Justin G Le; Stephen J Archibald; Shabana I Khan; Babu L Tekwani; M O Faruk Khan
Journal:  Bioorg Med Chem       Date:  2014-05-11       Impact factor: 3.641

2.  Ruthenium(II) arene complexes with chelating chloroquine analogue ligands: synthesis, characterization and in vitro antimalarial activity.

Authors:  Lotta Glans; Andreas Ehnbom; Carmen de Kock; Alberto Martínez; Jesús Estrada; Peter J Smith; Matti Haukka; Roberto A Sánchez-Delgado; Ebbe Nordlander
Journal:  Dalton Trans       Date:  2012-01-17       Impact factor: 4.390

3.  Synthesis, Antiplasmodial Activity, and β-Hematin Inhibition of Hydroxypyridone-Chloroquine Hybrids.

Authors:  Warren A Andayi; Timothy J Egan; Jiri Gut; Philip J Rosenthal; Kelly Chibale
Journal:  ACS Med Chem Lett       Date:  2013-05-20       Impact factor: 4.345

4.  The mechanism of antimalarial action of [Au(CQ)(PPh(3))]PF(6): structural effects and increased drug lipophilicity enhance heme aggregation inhibition at lipid/water interfaces.

Authors:  Maribel Navarro; William Castro; Alberto Martínez; Roberto A Sánchez Delgado
Journal:  J Inorg Biochem       Date:  2010-11-13       Impact factor: 4.155

Review 5.  Some nontoxic metal-based drugs for selected prevalent tropical pathogenic diseases.

Authors:  Saliu A Amolegbe; Caroline A Akinremi; Sheriff Adewuyi; Amudat Lawal; Mercy O Bamigboye; Joshua A Obaleye
Journal:  J Biol Inorg Chem       Date:  2016-11-30       Impact factor: 3.358

6.  Interactions of arene-Ru(II)-chloroquine complexes of known antimalarial and antitumor activity with human serum albumin (HSA) and transferrin.

Authors:  Alberto Martínez; Javier Suárez; Tiffany Shand; Richard S Magliozzo; Roberto A Sánchez-Delgado
Journal:  J Inorg Biochem       Date:  2011-01       Impact factor: 4.155

7.  Water Soluble Phosphane-Gold(I) Complexes. Applications as Recyclable Catalysts in a Three-component Coupling Reaction and as Antimicrobial and Anticancer Agents.

Authors:  Benelita T Elie; Chaya Levine; Iban Ubarretxena-Belandia; Armando Varela-Ramírez; Renato J Aguilera; Rafael Ovalle; María Contel
Journal:  Eur J Inorg Chem       Date:  2009-06-30       Impact factor: 2.524

8.  Beneficial effect of aurothiomalate on murine malaria.

Authors:  Ioana Alesutan; Diwakar Bobbala; Syed M Qadri; Adriana Estremera; Michael Föller; Florian Lang
Journal:  Malar J       Date:  2010-05-07       Impact factor: 2.979

9.  The antimalarial activity of Ru-chloroquine complexes against resistant Plasmodium falciparum is related to lipophilicity, basicity, and heme aggregation inhibition ability near water/n-octanol interfaces.

Authors:  Alberto Martínez; Chandima S K Rajapakse; Dalanda Jalloh; Cula Dautriche; Roberto A Sánchez-Delgado
Journal:  J Biol Inorg Chem       Date:  2009-04-03       Impact factor: 3.358

10.  Synthesis, characterization, and in vitro antimalarial and antitumor activity of new ruthenium(II) complexes of chloroquine.

Authors:  Chandima S K Rajapakse; Alberto Martínez; Becky Naoulou; Andrzej A Jarzecki; Liliana Suárez; Christiane Deregnaucourt; Véronique Sinou; Joseph Schrével; Elgilda Musi; Grazia Ambrosini; Gary K Schwartz; Roberto A Sánchez-Delgado
Journal:  Inorg Chem       Date:  2009-02-02       Impact factor: 5.165
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