Literature DB >> 9188637

Simian virus 40 T antigen can regulate p53-mediated transcription independent of binding p53.

J J Rushton1, D Jiang, A Srinivasan, J M Pipas, P D Robbins.   

Abstract

A simian virus 40 (SV40) T-antigen mutant containing only the N-terminal 136 amino acids, able to bind to Rb and p300 but not p53, partially inhibited p53-mediated transcription without affecting the ability of p53 to bind DNA. These results suggest that SV40 T antigen can regulate p53-mediated transcription either directly through protein-protein association or indirectly through interaction with factors which may function to confer p53-mediated transcription.

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Year:  1997        PMID： 9188637      PMCID： PMC191805          DOI： 10.1128/JVI.71.7.5620-5623.1997

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  25 in total

1.  T antigen is bound to a host protein in SV40-transformed cells.

Authors:  D P Lane; L V Crawford
Journal:  Nature       Date:  1979-03-15       Impact factor: 49.962

2.  Human p300 protein is a coactivator for the transcription factor MyoD.

Authors:  W Yuan; G Condorelli; M Caruso; A Felsani; A Giordano
Journal:  J Biol Chem       Date:  1996-04-12       Impact factor: 5.157

3.  Mutants with changes within or near a hydrophobic region of simian virus 40 large tumor antigen are defective for binding cellular protein p53.

Authors:  K W Peden; A Srinivasan; J M Farber; J M Pipas
Journal:  Virology       Date:  1989-01       Impact factor: 3.616

4.  Requirements for immortalization of primary mouse embryo fibroblasts probed with mutants bearing deletions in the 3' end of SV40 gene A.

Authors:  M J Tevethia; J M Pipas; T Kierstead; C Cole
Journal:  Virology       Date:  1988-01       Impact factor: 3.616

5.  The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53.

Authors:  M Scheffner; B A Werness; J M Huibregtse; A J Levine; P M Howley
Journal:  Cell       Date:  1990-12-21       Impact factor: 41.582

6.  Association of human papillomavirus types 16 and 18 E6 proteins with p53.

Authors:  B A Werness; A J Levine; P M Howley
Journal:  Science       Date:  1990-04-06       Impact factor: 47.728

7.  Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells.

Authors:  D I Linzer; A J Levine
Journal:  Cell       Date:  1979-05       Impact factor: 41.582

8.  TAF-like function of SV40 large T antigen.

Authors:  B Damania; J C Alwine
Journal:  Genes Dev       Date:  1996-06-01       Impact factor: 11.361

9.  The retinoblastoma-susceptibility gene product binds directly to the human TATA-binding protein-associated factor TAFII250.

Authors:  Z Shao; S Ruppert; P D Robbins
Journal:  Proc Natl Acad Sci U S A       Date:  1995-04-11       Impact factor: 11.205

10.  Phosphorylation of the adenovirus E1A-associated 300 kDa protein in response to retinoic acid and E1A during the differentiation of F9 cells.

Authors:  I Kitabayashi; R Eckner; Z Arany; R Chiu; G Gachelin; D M Livingston; K K Yokoyama
Journal:  EMBO J       Date:  1995-07-17       Impact factor: 11.598
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  11 in total

1.  The molecular chaperone activity of simian virus 40 large T antigen is required to disrupt Rb-E2F family complexes by an ATP-dependent mechanism.

Authors:  C S Sullivan; P Cantalupo; J M Pipas
Journal:  Mol Cell Biol       Date:  2000-09       Impact factor: 4.272

Review 2.  Brain tumors and polyomaviruses.

Authors:  Sidney Croul; Jessica Otte; Kamel Khalili
Journal:  J Neurovirol       Date:  2003-04       Impact factor: 2.643

3.  Defective DNA repair and cell cycle arrest in cells expressing Merkel cell polyomavirus T antigen.

Authors:  Stephanie K Demetriou; Katherine Ona-Vu; Erin M Sullivan; Tiffany K Dong; Shu-Wei Hsu; Dennis H Oh
Journal:  Int J Cancer       Date:  2012-05-29       Impact factor: 7.396

Review 4.  T antigens of simian virus 40: molecular chaperones for viral replication and tumorigenesis.

Authors:  Christopher S Sullivan; James M Pipas
Journal:  Microbiol Mol Biol Rev       Date:  2002-06       Impact factor: 11.056

5.  Binding to retinoblastoma pocket domain does not alter the inter-domain flexibility of the J domain of SV40 large T antigen.

Authors:  Christina K Williams; Sivaraja Vaithiyalingam; Michal Hammel; James Pipas; Walter J Chazin
Journal:  Arch Biochem Biophys       Date:  2011-12-29       Impact factor: 4.013

Review 6.  Chronic viral infection and primary central nervous system malignancy.

Authors:  Robert Saddawi-Konefka; John R Crawford
Journal:  J Neuroimmune Pharmacol       Date:  2010-04-13       Impact factor: 4.147

7.  p53-mediated regulation of proliferating cell nuclear antigen expression in cells exposed to ionizing radiation.

Authors:  J Xu; G F Morris
Journal:  Mol Cell Biol       Date:  1999-01       Impact factor: 4.272

8.  Cul7/p185/p193 binding to simian virus 40 large T antigen has a role in cellular transformation.

Authors:  Syed Hamid Ali; Jocelyn S Kasper; Takehiro Arai; James A DeCaprio
Journal:  J Virol       Date:  2004-03       Impact factor: 5.103

9.  Murine Gammaherpesvirus 68 LANA and SOX Homologs Counteract ATM-Driven p53 Activity during Lytic Viral Replication.

Authors:  Jeffrey M Sifford; James A Stahl; Eduardo Salinas; J Craig Forrest
Journal:  J Virol       Date:  2015-12-16       Impact factor: 5.103

10.  High-affinity Rb binding, p53 inhibition, subcellular localization, and transformation by wild-type or tumor-derived shortened Merkel cell polyomavirus large T antigens.

Authors:  Sophie Borchert; Manja Czech-Sioli; Friederike Neumann; Claudia Schmidt; Peter Wimmer; Thomas Dobner; Adam Grundhoff; Nicole Fischer
Journal:  J Virol       Date:  2013-12-26       Impact factor: 5.103
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