Literature DB >> 9185657

Plasma levels of adrenomedullin in primary and secondary pulmonary hypertension in patients <20 years of age.

M Yoshibayashi1, T Kamiya, K Kitamura, Y Saito, K Kangawa, T Nishikimi, H Matsuoka, T Eto, H Matsuo.   

Abstract

To elucidate the pathophysiologic significance of adrenomedullin in pulmonary hypertension, we measured plasma adrenomedullin-like immunoreactivity (AM-LI) concentrations in blood samples obtained from various sites during cardiac catheterization by using radioimmunoassay in patients with pulmonary hypertension in comparison with patients without pulmonary hypertension. In patients with pulmonary hypertension, plasma AM-LI concentrations were significantly elevated and there was a significant uptake of AM-LI in pulmonary circulation, indicating the involvement of adrenomedullin in the cardiovascular regulation of pulmonary circulation in pulmonary hypertension.

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Year:  1997        PMID： 9185657     DOI： 10.1016/s0002-9149(97)00195-1

Source DB:  PubMed          Journal:  Am J Cardiol        ISSN： 0002-9149            Impact factor:   2.778


  7 in total

1.  Plasma concentrations of adrenomedullin correlate with the extent of pulmonary hypertension in patients with mitral stenosis.

Authors:  T Nishikimi; S Nagata; T Sasaki; S Tomimoto; H Matsuoka; S Takishita; K Kitamura; A Miyata; H Matsuo; K Kangawa
Journal:  Heart       Date:  1997-10       Impact factor: 5.994

2.  Haemodynamic and hormonal effects of adrenomedullin in patients with pulmonary hypertension.

Authors:  N Nagaya; T Nishikimi; M Uematsu; T Satoh; H Oya; S Kyotani; F Sakamaki; K Ueno; N Nakanishi; K Miyatake; K Kangawa
Journal:  Heart       Date:  2000-12       Impact factor: 5.994

3.  Two molecular forms of adrenomedullin in congenital heart disease.

Authors:  K Watanabe; T Nishikimi; M Takamuro; K Yasuda; Y Ishikawa; S Tanabe; O Yamada; N Nagaya; H Matsuoka; K Kangawa; S Echigo
Journal:  Pediatr Cardiol       Date:  2003-09-04       Impact factor: 1.655

4.  Is adrenomedullin involved in the pathophysiology of persistent pulmonary hypertension of the newborn?

Authors:  Shinkichi Kamata; Masahumi Kamiyama; Noriaki Usui; Yasuhiro Kitayama; Hirohomi Okuyama; Akio Kubota; Kenji Kangawa
Journal:  Pediatr Surg Int       Date:  2003-12-23       Impact factor: 1.827

5.  Intratracheal gene transfer of adrenomedullin using polyplex nanomicelles attenuates monocrotaline-induced pulmonary hypertension in rats.

Authors:  Mariko Harada-Shiba; Itaru Takamisawa; Kanjiro Miyata; Takehiko Ishii; Nobuhiro Nishiyama; Keiji Itaka; Kenji Kangawa; Fumiki Yoshihara; Yujiro Asada; Kinta Hatakeyama; Noriya Nagaya; Kazunori Kataoka
Journal:  Mol Ther       Date:  2009-03-31       Impact factor: 11.454

6.  Role of adrenomedullin in congenital heart disease associated with pulmonary hypertension.

Authors:  Huiling Lu; Shaojiun Chen; Hongwei Wang; Peixuan Cheng
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2003

Review 7.  A Review of Adrenomedullin in Pediatric Patients: A Useful Biomarker.

Authors:  Anna Solé-Ribalta; Sara Bobillo-Pérez; Iolanda Jordan-García
Journal:  Children (Basel)       Date:  2022-08-06
  7 in total

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