Literature DB >> 918550

Crohn's disease. Recurrence after surgical treatment.

K Nygaard, O Fausa.   

Abstract

A series of 76 patients who have undergone surgical treatment for Crohn's disease is presented. In 14 of the patients surgery was performed for recurrence after previous resection. In total, 91 intestinal resections and one bypass--operation were carried out. Postoperative mortality comprised 4 patients (5.3%), and there were 4 late deaths. Sixty-six patients were followed up for periods ranging from 2 to 11 years, with a median of 4.0 years. Recurrence rates and reoperation rates were determined by actuarial analyses. The yearly recurrence rate seemed constant during the observation period, averaging 15.2%, and the cumulative recurrence rate was thus 77% after 9 years. The reoperation rate also seemed to be constant, and on the average 5.5% per year, and the cumulative reoperation per cent after 9 years was 45. There was no significant difference between cumulative recurrence rates after primary operations and after operations for recurrence. There was a significantly higher risk of relapse during the first year after non-radical excision of the diseased part of the gut than after radical excision. The majority of the patients were in good general condition at time of review; only 3 patients suffered from marked symptoms with reduced working capacity.

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Mesh:

Year:  1977        PMID: 918550     DOI: 10.3109/00365527709181336

Source DB:  PubMed          Journal:  Scand J Gastroenterol        ISSN: 0036-5521            Impact factor:   2.423


  13 in total

1.  European evidence based consensus on the diagnosis and management of Crohn's disease: special situations.

Authors:  R Caprilli; M A Gassull; J C Escher; G Moser; P Munkholm; A Forbes; D W Hommes; H Lochs; E Angelucci; A Cocco; B Vucelic; H Hildebrand; S Kolacek; L Riis; M Lukas; R de Franchis; M Hamilton; G Jantschek; P Michetti; C O'Morain; M M Anwar; J L Freitas; I A Mouzas; F Baert; R Mitchell; C J Hawkey
Journal:  Gut       Date:  2006-03       Impact factor: 23.059

2.  Through the endoscope balloon dilation of ileocolonic strictures: prognostic factors, complications, and effectiveness.

Authors:  Jörg C Hoffmann; Frank Heller; Siegbert Faiss; Bernd von Lampe; Anton J Kroesen; Ulrich Wahnschaffe; Jörg-Dieter Schulzke; Martin Zeitz; Christian Bojarski
Journal:  Int J Colorectal Dis       Date:  2008-03-13       Impact factor: 2.571

3.  Effect of resection margins on the recurrence of Crohn's disease in the small bowel. A randomized controlled trial.

Authors:  V W Fazio; F Marchetti; M Church; J R Goldblum; C Lavery; T L Hull; J W Milsom; S A Strong; J R Oakley; M Secic
Journal:  Ann Surg       Date:  1996-10       Impact factor: 12.969

4.  Endoscopy-based management decreases the risk of postoperative recurrences in Crohn's disease.

Authors:  Anne-Laure Boucher; Bruno Pereira; Stéphanie Decousus; Marion Goutte; Felix Goutorbe; Anne Dubois; Johan Gagniere; Corinne Borderon; Juliette Joubert; Denis Pezet; Michel Dapoigny; Pierre J Déchelotte; Gilles Bommelaer; Anthony Buisson
Journal:  World J Gastroenterol       Date:  2016-06-07       Impact factor: 5.742

5.  Changes in small intestinal epithelial expression of MHC class II antigen after terminal ileal resection for Crohn's disease.

Authors:  K Geboes; P Rutgeerts; F Penninckx; V Desmet; G Vantrappen
Journal:  Int J Colorectal Dis       Date:  1988-06       Impact factor: 2.571

6.  Segmental versus total colectomy for large bowel Crohn's disease.

Authors:  H S Stern; S M Goldberg; D A Rothenberger; S Nivatvongs; J Schottler; C Christenson; F Nemer; E Balcos
Journal:  World J Surg       Date:  1984-02       Impact factor: 3.352

7.  Postoperative recurrence in Crohn's disease. The effect of the initial length of bowel resection and operative procedure.

Authors:  L Ellis; P Calhoun; D L Kaiser; L E Rudolf; J B Hanks
Journal:  Ann Surg       Date:  1984-03       Impact factor: 12.969

8.  Factors influencing postoperative recurrence of Crohn's disease in childhood.

Authors:  A M Griffiths; D E Wesson; B Shandling; M Corey; P M Sherman
Journal:  Gut       Date:  1991-05       Impact factor: 23.059

Review 9.  Postsurgical recurrence of ileal Crohn's disease: an update on risk factors and intervention points to a central role for impaired host-microflora homeostasis.

Authors:  Michael F Cunningham; Neil G Docherty; J Calvin Coffey; John P Burke; P Ronan O'Connell
Journal:  World J Surg       Date:  2010-07       Impact factor: 3.352

10.  Primary and recurrent Crohn's disease. Experience with 1379 patients.

Authors:  F Michelassi; T Balestracci; R Chappell; G E Block
Journal:  Ann Surg       Date:  1991-09       Impact factor: 12.969

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