Literature DB >> 9184801

Inhibition of a Porphyromonas gingivalis colonizing factor between Actinomyces viscosus ATCC 19246 by monoclonal antibodies against recombinant 40-kDa outer-membrane protein.

S Saito1, K Hiratsuka, M Hayakawa, H Takiguchi, Y Abiko.   

Abstract

1. Porphyromonas gingivalis, an important pathogen in human periodontal disease, aggregates with Actinomyces viscosus ATCC 19246. 2. Monoclonal antibodies (mAbs) against purified recombinant 40-kDa outer-membrane protein (r40-kDa, OMP) of P. gingivalis 381 inhibited its coaggregation with A. viscosus ATCC 19246 in a dose-dependent manner. 3. Five mAb clones against r40-kDa OMP were selected. The isotype of the five was IgG1. 4. Pg-ompA2 inhibited the coaggregation of several strains of P. gingivalis with A. viscosus ATCC 19246 cells.

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Year:  1997        PMID： 9184801     DOI： 10.1016/s0306-3623(96)00366-7

Source DB:  PubMed          Journal:  Gen Pharmacol        ISSN： 0306-3623


  7 in total

1.  Oral immunization with Porphyromonas gingivalis outer membrane protein and CpGoligodeoxynucleotides elicits T helper 1 and 2 cytokines for enhanced protective immunity.

Authors:  Chenlu Liu; Tomomi Hashizume; Tomoko Kurita-Ochiai; Kohtaro Fujihashi; Masafumi Yamamoto
Journal:  Mol Oral Microbiol       Date:  2010-06       Impact factor: 3.563

2.  Nasal immunization with Porphyromonas gingivalis outer membrane protein decreases P. gingivalis-induced atherosclerosis and inflammation in spontaneously hyperlipidemic mice.

Authors:  Y Koizumi; T Kurita-Ochiai; S Oguchi; M Yamamoto
Journal:  Infect Immun       Date:  2008-04-21       Impact factor: 3.441

3.  Nasal vaccination with the 40-kilodalton outer membrane protein of Porphyromonas gingivalis and a nontoxic chimeric enterotoxin adjuvant induces long-term protective immunity with reduced levels of immunoglobulin E antibodies.

Authors:  Fumiki Momoi; Tomomi Hashizume; Tomoko Kurita-Ochiai; Yoshikazu Yuki; Hiroshi Kiyono; Masafumi Yamamoto
Journal:  Infect Immun       Date:  2008-04-14       Impact factor: 3.441

4.  Vaccines against periodontitis: a forward-looking review.

Authors:  Jeom-Il Choi; Gregory J Seymour
Journal:  J Periodontal Implant Sci       Date:  2010-08-30       Impact factor: 2.614

5.  Characterization of hemin-binding protein 35 (HBP35) in Porphyromonas gingivalis: its cellular distribution, thioredoxin activity and role in heme utilization.

Authors:  Mikio Shoji; Yasuko Shibata; Teruaki Shiroza; Hideharu Yukitake; Benjamin Peng; Yu-Yen Chen; Keiko Sato; Mariko Naito; Yoshimitsu Abiko; Eric C Reynolds; Koji Nakayama
Journal:  BMC Microbiol       Date:  2010-05-25       Impact factor: 3.605

6.  Por secretion system-dependent secretion and glycosylation of Porphyromonas gingivalis hemin-binding protein 35.

Authors:  Mikio Shoji; Keiko Sato; Hideharu Yukitake; Yoshio Kondo; Yuka Narita; Tomoko Kadowaki; Mariko Naito; Koji Nakayama
Journal:  PLoS One       Date:  2011-06-22       Impact factor: 3.240

Review 7.  Porphyromonas gingivalis: An Overview of Periodontopathic Pathogen below the Gum Line.

Authors:  Kah Yan How; Keang Peng Song; Kok Gan Chan
Journal:  Front Microbiol       Date:  2016-02-09       Impact factor: 5.640
  7 in total

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