Literature DB >> 9181680

Synthesis and biological activities of higher homologues of retinoic acid.

J Y Winum1, M Kamal, H Defacque, T Commes, C Chavis, M Lucas, J Marti, J L Montero.   

Abstract

Homoretinoic and bishomoretinoic acid have been synthesized. Fast reaction under ultrasonic activation (Wolff rearrangement, saponification) produced compounds in high yields. Only the bishomo analogue exhibits a significative activity alone and a synergistic effect with vitamin D3 on the differentiation of U937 leukemic cell line.

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Year:  1997        PMID： 9181680

Source DB:  PubMed          Journal:  Farmaco        ISSN： 0014-827X


  5 in total

Review 1.  The formation, occurrence, and function of β-apocarotenoids: β-carotene metabolites that may modulate nuclear receptor signaling.

Authors:  Earl H Harrison; Carlo dela Sena; Abdulkerim Eroglu; Matthew K Fleshman
Journal:  Am J Clin Nutr       Date:  2012-10-10       Impact factor: 7.045

Review 2.  Lycopene metabolism and its biological significance.

Authors:  Xiang-Dong Wang
Journal:  Am J Clin Nutr       Date:  2012-10-10       Impact factor: 7.045

3.  Enzymatic formation of apo-carotenoids from the xanthophyll carotenoids lutein, zeaxanthin and β-cryptoxanthin by ferret carotene-9',10'-monooxygenase.

Authors:  Jonathan R Mein; Gregory G Dolnikowski; Hansgeorg Ernst; Robert M Russell; Xiang-Dong Wang
Journal:  Arch Biochem Biophys       Date:  2010-11-21       Impact factor: 4.013

4.  The biochemical characterization of ferret carotene-9',10'-monooxygenase catalyzing cleavage of carotenoids in vitro and in vivo.

Authors:  Kang-Quan Hu; Chun Liu; Hansgeorg Ernst; Norman I Krinsky; Robert M Russell; Xiang-Dong Wang
Journal:  J Biol Chem       Date:  2006-05-03       Impact factor: 5.157

Review 5.  Carotenoid metabolism in mammals, including man: formation, occurrence, and function of apocarotenoids.

Authors:  Abdulkerim Eroglu; Earl H Harrison
Journal:  J Lipid Res       Date:  2013-05-10       Impact factor: 5.922
  5 in total

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