Literature DB >> 9180279

Serine-threonine protein kinase activity of Elm1p, a regulator of morphologic differentiation in Saccharomyces cerevisiae.

C M Koehler1, A M Myers.   

Abstract

The Saccharomyces cerevisiae gene ELM1 regulates morphologic differentiation and its nucleotide sequence predicts a novel protein kinase. Elm1p was expressed in yeast and insect cells and purified. Elm1p displayed protein kinase activity in autophosphorylation assays and towards exogenous substrates. Serine and threonine residues were identified as the acceptors in these reactions. These data together with previous genetic analysis of ELM1 function indicate that phosphorylation on serine and/or threonine residues of a particular substrate or set of substrates by Elm1p is required for repression of the filamentous growth differentiation state.

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Year:  1997        PMID： 9180279     DOI： 10.1016/s0014-5793(97)00401-8

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  10 in total

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Journal:  Proc Natl Acad Sci U S A       Date:  2000-12-05       Impact factor: 11.205

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3.  Snf1 kinase complexes with different beta subunits display stress-dependent preferences for the three Snf1-activating kinases.

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4.  Control of Saccharomyces cerevisiae filamentous growth by cyclin-dependent kinase Cdc28.

Authors:  N P Edgington; M J Blacketer; T A Bierwagen; A M Myers
Journal:  Mol Cell Biol       Date:  1999-02       Impact factor: 4.272

5.  Cell cycle-dependent phosphorylation and ubiquitination of a G protein alpha subunit.

Authors:  Matthew P Torres; Sarah T Clement; Steven D Cappell; Henrik G Dohlman
Journal:  J Biol Chem       Date:  2011-04-26       Impact factor: 5.157

6.  Elm1 kinase activates the spindle position checkpoint kinase Kin4.

Authors:  Ayse Koca Caydasi; Bahtiyar Kurtulmus; Maria I L Orrico; Astrid Hofmann; Bashar Ibrahim; Gislene Pereira
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Review 7.  Septin-Associated Protein Kinases in the Yeast Saccharomyces cerevisiae.

Authors:  Adam M Perez; Gregory C Finnigan; Françoise M Roelants; Jeremy Thorner
Journal:  Front Cell Dev Biol       Date:  2016-11-01

8.  Forward and reverse genetic dissection of morphogenesis identifies filament-competent Candida auris strains.

Authors:  Darian J Santana; Teresa R O'Meara
Journal:  Nat Commun       Date:  2021-12-10       Impact factor: 14.919

9.  Budding yeast dma proteins control septin dynamics and the spindle position checkpoint by promoting the recruitment of the Elm1 kinase to the bud neck.

Authors:  Laura Merlini; Roberta Fraschini; Barbara Boettcher; Yves Barral; Giovanna Lucchini; Simonetta Piatti
Journal:  PLoS Genet       Date:  2012-04-26       Impact factor: 5.917

10.  A novel genetic screen implicates Elm1 in the inactivation of the yeast transcription factor SBF.

Authors:  Emily N Manderson; Mohan Malleshaiah; Stephen W Michnick
Journal:  PLoS One       Date:  2008-01-30       Impact factor: 3.240
  10 in total

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