| Literature DB >> 9178477 |
I Mastroeni1, A M Patti, A Fabrizi, A L Santi, A M Manduca, N Vescia, S Squarcione, G M Fara.
Abstract
The immunity against poliomyelitis in 1000 subjects 13-14 years old was evaluated. Neutralizing antibodies against poliovirus type 1, 2 and 3 were detected in 97.6%, 95.8% and 70% of samples, respectively. 3/1000 (0.3%) subjects were simultaneously seronegative to the three types. WHO does not suggest a protective level of International Units (IU), but our data indicate that such level is 0.45 IU for polio type 1, 0.65 IU for the type 2 and 0.138 for the type 3. A booster dose of vaccine in adolescence to ensure personal and herd immunity is recommended.Entities:
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Year: 1997 PMID： 9178477 DOI： 10.1016/s0264-410x(96)00208-3
Source DB: PubMed Journal: Vaccine ISSN： 0264-410X Impact factor: 3.641