| Literature DB >> 9178251 |
B E Scanley1, R P Kennan, S Cannan, P Skudlarski, R B Innis, J C Gore.
Abstract
An animal model of sensory activation using fMRI at 2.0 T has been developed, demonstrating that fMRI studies on animals need not be limited to high field magnets. These methods produced reliable image intensity changes of 2% using median nerve stimulation in rats at 3 Hz and propofol as the anesthetic agent. At 6 Hz the activation was slightly but not statistically significantly greater. The feasibility of fMRI studies in animals using propofol suggests that it may be a useful anesthetic for fMRI studies in agitated adult patients or in children.Entities:
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Year: 1997 PMID： 9178251 DOI： 10.1002/mrm.1910370625
Source DB: PubMed Journal: Magn Reson Med ISSN： 0740-3194 Impact factor: 4.668