Literature DB >> 917801

[The determination of amanitines in the serum of patients poisoned by amanita phalloides (author's transl)].

C Busi, L Fiume, D Costantino, M Borroni, G Ambrosino, A Olivotto, D Bernardini.   

Abstract

The serum of patients suffering from Amanita phalloides poisoning was analysed in order to determine whether amanitines, which are the principal toxins of this fungus, were still present in the blood at the time of hospitalisation. In addition, the authors measured the concentrations of amanitines in the blood of dogs at different intervals after the ingestion of a fatal dose of Amanita phalloides. Amanitines were detected in the serum of 9 patients out of 16. This discovery, together with the finding that, in the dog, very low concentrations of amanitines in the blood are associated with fatal cellular lesions, suggests the need for very prompt action in order to eliminate these toxins from the blood as soon as the diagnosis of poisoning is suspected.

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Year:  1977        PMID: 917801

Source DB:  PubMed          Journal:  Nouv Presse Med        ISSN: 0301-1518


  6 in total

Review 1.  Hepatotoxic mushroom poisoning: diagnosis and management.

Authors:  J Piqueras
Journal:  Mycopathologia       Date:  1989-02       Impact factor: 2.574

2.  Fatal mushroom poisoning in Barcelona, 1986-1988.

Authors:  P Sanz; R Reig; J Piqueras; G Marti; J Corbella
Journal:  Mycopathologia       Date:  1989-12       Impact factor: 2.574

3.  Amatoxin poisoning in northern California, 1982-1983.

Authors:  S M Pond; K R Olson; O F Woo; J D Osterloh; R E Ward; D A Kaufman; R R Moody
Journal:  West J Med       Date:  1986-08

4.  Toxicokinetics of labeled amatoxins in the dog.

Authors:  H Faulstich; A Talas; H H Wellhöner
Journal:  Arch Toxicol       Date:  1985-01       Impact factor: 5.153

5.  Clinical findings and follow-up evaluation of an outbreak of mushroom poisoning--survey of Amanita phalloides poisoning.

Authors:  R Fantozzi; F Ledda; L Caramelli; F Moroni; P Blandina; E Masini; P Botti; S Peruzzi; M Zorn; P F Mannaioni
Journal:  Klin Wochenschr       Date:  1986-01-02

6.  Analysis of α- and β-amanitin in Human Plasma at Subnanogram per Milliliter Levels by Reversed Phase Ultra-High Performance Liquid Chromatography Coupled to Orbitrap Mass Spectrometry.

Authors:  Thomas P Bambauer; Lea Wagmann; Armin A Weber; Markus R Meyer
Journal:  Toxins (Basel)       Date:  2020-10-23       Impact factor: 4.546

  6 in total

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