Literature DB >> 9176637

What exactly are genomes, genotypes and phenotypes? And what about phenomes?

M Mahner1, M Kary.   

Abstract

The fundamental concepts of genome, genotype and phenotype are not defined in a satisfactory manner within the biological literature. Not only are there inconsistencies in usage between various authors, but even individual authors do not use these concepts in a consistent manner within their own writings. We have found at least five different notions of genome, seven of genotype, and five of phenotype current in the literature. Our goal is to clarify this situation by (a) defining clearly and precisely the notions of genetic complement, genome, genotype, phenetic complement, and phenotype; (b) examining that of phenome; and (c) analysing the logical structure of this family of concepts.

Mesh:

Year:  1997        PMID: 9176637     DOI: 10.1006/jtbi.1996.0335

Source DB:  PubMed          Journal:  J Theor Biol        ISSN: 0022-5193            Impact factor:   2.691


  28 in total

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Journal:  Plant Mol Biol       Date:  2002-01       Impact factor: 4.076

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Review 5.  Stochastic developmental variation, an epigenetic source of phenotypic diversity with far-reaching biological consequences.

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Journal:  J Biosci       Date:  2015-03       Impact factor: 1.826

Review 6.  Expression profiling of the mouse early embryo: reflections and perspectives.

Authors:  Minoru S H Ko
Journal:  Dev Dyn       Date:  2006-09       Impact factor: 3.780

7.  Cancer heterogeneity and multilayer spatial evolutionary games.

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Journal:  Biol Direct       Date:  2016-10-13       Impact factor: 4.540

Review 8.  Fishing forward and reverse: Advances in zebrafish phenomics.

Authors:  Ricardo Fuentes; Joaquín Letelier; Benjamin Tajer; Leonardo E Valdivia; Mary C Mullins
Journal:  Mech Dev       Date:  2018-08-18       Impact factor: 1.882

Review 9.  Whole-Organism Cellular Pathology: A Systems Approach to Phenomics.

Authors:  K C Cheng; S R Katz; A Y Lin; X Xin; Y Ding
Journal:  Adv Genet       Date:  2016-07-29       Impact factor: 1.944

10.  Strategies for the study of neuropsychiatric disorders using endophenotypes in developing countries: a potential databank from china.

Authors:  Raymond C K Chan; Irving I Gottesman; Xiaojia Ge; Pak C Sham
Journal:  Front Hum Neurosci       Date:  2010-10-28       Impact factor: 3.169

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