Literature DB >> 9175621

Identification of pore-forming subunit of P-type calcium channels: an antisense study on rat cerebellar Purkinje cells in culture.

S E Gillard1, S G Volsen, W Smith, R E Beattie, D Bleakman, D Lodge.   

Abstract

Treatment of cerebellar neurones in culture with an antisense oligonucleotide (ODN) against alpha1A, reduced the whole-cell P-type calcium channel current relative to mismatch ODN treated controls (p < 0.001). Therefore, AgaIVA (50 nM) reduced whole-cell calcium current in mismatch and antisense treated cells by 70 +/- 4 and 19 +/- 3%, respectively.

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Year:  1997        PMID： 9175621     DOI： 10.1016/s0028-3908(97)00046-4

Source DB:  PubMed          Journal:  Neuropharmacology        ISSN： 0028-3908            Impact factor:   5.250


  20 in total

1.  Properties of Q-type calcium channels in neostriatal and cortical neurons are correlated with beta subunit expression.

Authors:  P G Mermelstein; R C Foehring; T Tkatch; W J Song; G Baranauskas; D J Surmeier
Journal:  J Neurosci       Date:  1999-09-01       Impact factor: 6.167

2.  Ablation of P/Q-type Ca(2+) channel currents, altered synaptic transmission, and progressive ataxia in mice lacking the alpha(1A)-subunit.

Authors:  K Jun; E S Piedras-Rentería; S M Smith; D B Wheeler; S B Lee; T G Lee; H Chin; M E Adams; R H Scheller; R W Tsien; H S Shin
Journal:  Proc Natl Acad Sci U S A       Date:  1999-12-21       Impact factor: 11.205

3.  Differential plasma membrane targeting of voltage-dependent calcium channel subunits expressed in a polarized epithelial cell line.

Authors:  N L Brice; A C Dolphin
Journal:  J Physiol       Date:  1999-03-15       Impact factor: 5.182

4.  Whole-cell and single-channel analysis of P-type calcium currents in cerebellar Purkinje cells of leaner mutant mice.

Authors:  L S Dove; L C Abbott; W H Griffith
Journal:  J Neurosci       Date:  1998-10-01       Impact factor: 6.167

5.  Increased expression of alpha 1A Ca2+ channel currents arising from expanded trinucleotide repeats in spinocerebellar ataxia type 6.

Authors:  E S Piedras-Renteria; K Watase; N Harata; O Zhuchenko; H Y Zoghbi; C C Lee; R W Tsien
Journal:  J Neurosci       Date:  2001-12-01       Impact factor: 6.167

6.  Calcium channel subtypes contributing to acetylcholine release from normal, 4-aminopyridine-treated and myasthenic syndrome auto-antibodies-affected neuromuscular junctions.

Authors:  F Giovannini; E Sher; R Webster; J Boot; B Lang
Journal:  Br J Pharmacol       Date:  2002-08       Impact factor: 8.739

7.  Kv3.3 channels harbouring a mutation of spinocerebellar ataxia type 13 alter excitability and induce cell death in cultured cerebellar Purkinje cells.

Authors:  Tomohiko Irie; Yasunori Matsuzaki; Yuko Sekino; Hirokazu Hirai
Journal:  J Physiol       Date:  2013-11-11       Impact factor: 5.182

8.  N-type and P/Q-type calcium channels regulate differentially the release of noradrenaline, ATP and beta-NAD in blood vessels.

Authors:  Lisa M Smyth; Ilia A Yamboliev; Violeta N Mutafova-Yambolieva
Journal:  Neuropharmacology       Date:  2008-09-25       Impact factor: 5.250

Review 9.  Homeostatic compensation maintains Ca2+ signaling functions in Purkinje neurons in the leaner mutant mouse.

Authors:  David Murchison; Leonard S Dove; Louise C Abbott; William H Griffith
Journal:  Cerebellum       Date:  2002-04       Impact factor: 3.847

10.  Altered calcium channel currents in Purkinje cells of the neurological mutant mouse leaner.

Authors:  N M Lorenzon; C M Lutz; W N Frankel; K G Beam
Journal:  J Neurosci       Date:  1998-06-15       Impact factor: 6.167
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