| Literature DB >> 9171918 |
S Papa1, F Guerrieri, N Capitanio.
Abstract
Evidence is available showing that the coupling efficiency of the proton pump in cytochrome c oxidase of mitochondria can under certain conditions decrease significantly below the maximum attainable value. The view is developed that slips in the proton pump of cytochrome c oxidase represent an intrinsic switch mechanism which regulates the relative contribution of energy transfer and respiratory protection against oxygen toxicity by the oxidase.Entities:
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Year: 1997 PMID: 9171918 DOI: 10.1023/a:1027331116866
Source DB: PubMed Journal: Biosci Rep ISSN: 0144-8463 Impact factor: 3.840