BACKGROUND: Dysphagia is the cardinal symptom of oesophageal cancer, yet many patients present late. This study examined prospectively the interval between onset of dysphagia and treatment and identified reasons for delay. METHODS:Patients with histologically confirmed oesophageal carcinoma were questioned about duration of symptoms and about each step of their diagnostic work-up. Delay was estimated from date of onset of symptoms to definitive treatment. RESULTS:Median delay was 15 weeks for 78 patients with dysphagia, and 17 weeks for 22 patients with other symptoms. The most frequent cause of delay was late presentation to the family doctor (44 per cent). For patients treated with surgery alone there was a trend towards more advanced stage of disease with longer delay to treatment, but no correlation with survival (P = 0.25). CONCLUSION: Lack of awareness of the sinister significance of dysphagia is the most important cause for delay in presentation of patients with oesophageal cancer.
RCT Entities:
BACKGROUND:Dysphagia is the cardinal symptom of oesophageal cancer, yet many patients present late. This study examined prospectively the interval between onset of dysphagia and treatment and identified reasons for delay. METHODS:Patients with histologically confirmed oesophageal carcinoma were questioned about duration of symptoms and about each step of their diagnostic work-up. Delay was estimated from date of onset of symptoms to definitive treatment. RESULTS: Median delay was 15 weeks for 78 patients with dysphagia, and 17 weeks for 22 patients with other symptoms. The most frequent cause of delay was late presentation to the family doctor (44 per cent). For patients treated with surgery alone there was a trend towards more advanced stage of disease with longer delay to treatment, but no correlation with survival (P = 0.25). CONCLUSION: Lack of awareness of the sinister significance of dysphagia is the most important cause for delay in presentation of patients with oesophageal cancer.
Authors: John F Gibbs; Ashwani Rajput; Krishdeep S Chadha; Wade G Douglas; Hank Hill; Chukwumere Nwogu; Hector R Nava; Michael S Sabel Journal: J Natl Med Assoc Date: 2007-06 Impact factor: 1.798
Authors: E Visser; A G Leeftink; P S N van Rossum; S Siesling; R van Hillegersberg; J P Ruurda Journal: Ann Surg Oncol Date: 2016-03-24 Impact factor: 5.344
Authors: Brechtje A Grotenhuis; Pieter van Hagen; Bas P L Wijnhoven; Manon C W Spaander; Hugo W Tilanus; Jan J B van Lanschot Journal: J Gastrointest Surg Date: 2009-12-10 Impact factor: 3.452