Literature DB >> 9170293

Identification of the novel antimicrobial fatty acid (5Z,9Z)-14-methyl-5,9-pentadecadienoic acid in Eunicea succinea.

N M Carballeira1, E D Reyes, A Sostre, A D Rodríguez, J L Rodríguez, F A González.   

Abstract

The phospholipid fatty acid composition of Eunicea succinea was investigated, and the novel (5Z,9Z)-14-methyl-5,9-pentadecadienoic acid was identified. Structural characterization was accomplished by means of mass spectrometry of its pyrrolidide derivative, NMR, FT1R, and total synthesis. Other interesting phospholipid fatty acids in E. succinea were the tetracosapolyenoic acids 6,9,12,15,18,21-tetracosahexaenoic acid (24:6) and 6,9,12,15,18-tetracosapentaenoic acids (24:5). The title compound was particularly active against Gram-positive bacteria such as Staphylococcus aureus (MIC 0.24 mumol/mL) and Streptococcus faecalis (MIC 0.16 mumol/ mL).

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Year:  1997        PMID: 9170293     DOI: 10.1021/np970034t

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  7 in total

1.  (4Z,15Z)-Octadecadienoic Acid Inhibits Glycogen Synthase Kinase-3β and Glucose Production in H4IIE Cells.

Authors:  Jun Yoshida; Shota Uesugi; Tetsuaki Kawamura; Ken-Ichi Kimura; Dawei Hu; Shuang Xia; Naoki Toyooka; Masao Ohnishi; Hideki Kawashima
Journal:  Lipids       Date:  2017-02-13       Impact factor: 1.880

Review 2.  Antimicrobial Lipids from Plants and Marine Organisms: An Overview of the Current State-of-the-Art and Future Prospects.

Authors:  Eliana Alves; Marina Dias; Diana Lopes; Adelaide Almeida; Maria do Rosário Domingues; Felisa Rey
Journal:  Antibiotics (Basel)       Date:  2020-07-24

3.  Novel Odd-Chain Fatty Acids with a Terminal Double Bond in Ovaries of the Limpet Cellana toreuma.

Authors:  Hideki Kawashima; Masao Ohnishi
Journal:  Lipids       Date:  2017-02-23       Impact factor: 1.880

4.  A new cytotoxic fatty acid (5Z,9Z)-22-methyl-5,9-tetracosadienoic acid and the sterols from the far eastern sponge Geodinella robusta.

Authors:  Tatyana N Makarieva; Elena A Santalova; Irina A Gorshkova; Andrei S Dmitrenok; Alla G Guzii; Vladimir I Gorbach; Vassilii I Svetashev; Valentin A Stonik
Journal:  Lipids       Date:  2002-01       Impact factor: 1.880

Review 5.  Marine unsaturated fatty acids: structures, bioactivities, biosynthesis and benefits.

Authors:  Yingfang Lu; Yinning Chen; Yulin Wu; Huili Hao; Wenjing Liang; Jun Liu; Riming Huang
Journal:  RSC Adv       Date:  2019-10-31       Impact factor: 4.036

Review 6.  Slime molds as a valuable source of antimicrobial agents.

Authors:  Vida Tafakori
Journal:  AMB Express       Date:  2021-06-23       Impact factor: 3.298

7.  Lipids and fatty acids of nudibranch mollusks: potential sources of bioactive compounds.

Authors:  Natalia V Zhukova
Journal:  Mar Drugs       Date:  2014-08-19       Impact factor: 5.118

  7 in total

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