Literature DB >> 9169797

Modulation of neutrophil superoxide response and intracellular diacylglyceride levels by the bacterial pigment pyocyanin.

M Muller1, T C Sorrell.   

Abstract

Low concentrations of pyocyanin are reported to enhance superoxide production by human neutrophils exposed to various stimuli, yet the mechanism remains unknown. Using lucigenin-enhanced chemiluminescence, we examined the kinetics of the neutrophil superoxide response in the presence of pyocyanin. At all concentrations (12.5 to 200 microM), pyocyanin decreased the peak superoxide response while prolonging the duration of the response. The prolonged response may be associated with an observed increase in intracellular diacylglyceride levels due to pyocyanin exposure.

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Year:  1997        PMID： 9169797      PMCID： PMC175349          DOI： 10.1128/iai.65.6.2483-2487.1997

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  31 in total

1.  On radical production by PMA-stimulated neutrophils as monitored by luminol-amplified chemiluminescence.

Authors:  A Samuni; C M Krishna; J Cook; C D Black; A Russo
Journal:  Free Radic Biol Med       Date:  1991       Impact factor: 7.376

2.  Production of leukotriene B4 and 5-hydroxyeicosatetraenoic acid by human neutrophils is inhibited by Pseudomonas aeruginosa phenazine derivatives.

Authors:  M Muller; T C Sorrell
Journal:  Infect Immun       Date:  1991-09       Impact factor: 3.441

3.  Inhibition of normal and malignant cell proliferation by pyocyanine and 1-hydroxyphenazine.

Authors:  R U Sorensen; D N Fredricks; R L Waller
Journal:  Antibiot Chemother (1971)       Date:  1991

4.  Activation of neutrophils NADPH oxidase by PMA: cytosol activity is translocated in phorbol-primed neutrophils.

Authors:  T Umei; N Ohhara; S Okamura; M Harada; M Nakao; T Shirai; Y Niho
Journal:  Int J Biochem       Date:  1993-05

5.  Proinflammatory interactions of pyocyanin and 1-hydroxyphenazine with human neutrophils in vitro.

Authors:  G J Ras; R Anderson; G W Taylor; J E Savage; E Van Niekerk; R Wilson; P J Cole
Journal:  J Infect Dis       Date:  1990-07       Impact factor: 5.226

6.  Effects of pyocyanine, a phenazine dye from Pseudomonas aeruginosa, on oxidative burst and bacterial killing in human neutrophils.

Authors:  P K Müller; K Krohn; P F Mühlradt
Journal:  Infect Immun       Date:  1989-09       Impact factor: 3.441

7.  Activation of NADPH oxidase and phospholipase D in permeabilized human neutrophils. Correlation between oxidase activation and phosphatidic acid production.

Authors:  S A Bauldry; K L Elsey; D A Bass
Journal:  J Biol Chem       Date:  1992-12-15       Impact factor: 5.157

8.  Luminol chemiluminescence and active oxygen generation by activated neutrophils.

Authors:  R Takahashi; K Edashige; E F Sato; M Inoue; T Matsuno; K Utsumi
Journal:  Arch Biochem Biophys       Date:  1991-03       Impact factor: 4.013

9.  Leukotriene B4 omega-oxidation by human polymorphonuclear leukocytes is inhibited by pyocyanin, a phenazine derivative produced by Pseudomonas aeruginosa.

Authors:  M Muller; T C Sorrell
Journal:  Infect Immun       Date:  1992-06       Impact factor: 3.441

10.  Comparison of diglyceride production from choline-containing phosphoglycerides in human neutrophils stimulated with N-formylmethionyl-leucylphenylalanine, ionophore A23187 or phorbol 12-myristate 13-acetate.

Authors:  M C Chabot; L C McPhail; R L Wykle; D A Kennerly; C E McCall
Journal:  Biochem J       Date:  1992-09-15       Impact factor: 3.857
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  3 in total

1.  The Pseudomonas toxin pyocyanin inhibits the dual oxidase-based antimicrobial system as it imposes oxidative stress on airway epithelial cells.

Authors:  Balázs Rada; Kristen Lekstrom; Sorin Damian; Corinne Dupuy; Thomas L Leto
Journal:  J Immunol       Date:  2008-10-01       Impact factor: 5.422

2.  Pseudomonas aeruginosa exotoxin pyocyanin causes cystic fibrosis airway pathogenesis.

Authors:  Charles C Caldwell; Yi Chen; Holly S Goetzmann; Yonghua Hao; Michael T Borchers; Daniel J Hassett; Lisa R Young; Dmitri Mavrodi; Linda Thomashow; Gee W Lau
Journal:  Am J Pathol       Date:  2009-11-05       Impact factor: 4.307

3.  Redox warfare between airway epithelial cells and Pseudomonas: dual oxidase versus pyocyanin.

Authors:  Balázs Rada; Thomas L Leto
Journal:  Immunol Res       Date:  2009       Impact factor: 2.829
  3 in total

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