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Literature DB >> 9169790

Interleukin-6 production by human monocytes stimulated with Cryptococcus neoformans components.

D Delfino¹, L Cianci, E Lupis, A Celeste, M L Petrelli, F Curró, V Cusumano, G Teti.

Abstract

In order to ascertain if Cryptococcus neoformans components can induce interleukin-6 (IL-6) production, we stimulated human whole blood with purified capsular products. Their potencies in stimulating IL-6 release were mannoproteins > galactoxylomannan = glucuronoxylomannan > alpha(1-3)glucan. IL-6 production was tumor necrosis factor alpha independent and required the presence of monocytes and plasma. Since IL-6 can stimulate replication of the human immunodeficiency virus in monocytic cells, these findings may be clinically relevant.

Entities: Chemical Gene Species

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Year: 1997 PMID： 9169790 PMCID： PMC175342 DOI： 10.1128/iai.65.6.2454-2456.1997

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

19 in total

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24 in total

1. Human monocyte receptors involved in tumor necrosis factor responses to group B streptococcal products.

Authors: M Cuzzola; G Mancuso; C Beninati; C Biondo; C von Hunolstein; G Orefici; T Espevik; T H Flo; G Teti
Journal: Infect Immun Date: 2000-02 Impact factor: 3.441

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Authors: Zong Liang Chang; Dale Netski; Peter Thorkildson; Thomas R Kozel
Journal: Infect Immun Date: 2006-01 Impact factor: 3.441

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Authors: Juliana Rizzo; Débora L Oliveira; Luna S Joffe; Guanggan Hu; Felipe Gazos-Lopes; Fernanda L Fonseca; Igor C Almeida; Susana Frases; James W Kronstad; Marcio L Rodrigues
Journal: Eukaryot Cell Date: 2013-12-13

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Journal: Virulence Date: 2010-11-01 Impact factor: 5.882

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Journal: Infect Immun Date: 2006-09 Impact factor: 3.441