Literature DB >> 9169687

Stereotactic core biopsy of calcifications highly suggestive of malignancy.

L Liberman1, L R LaTrenta, K J Van Zee, E A Morris, A F Abramson, D D Dershaw.   

Abstract

PURPOSE: To assess stereotactic core biopsy for evaluation of Breast Imaging Reporting and Data System (BI-RADS) category 5 calcifications (highly suggestive of malignancy).
MATERIALS AND METHODS: Retrospective review of mammograms revealed 31 women (aged 34-86 years) with BI-RADS category 5 calcifications who underwent 14-gauge stereotactic core biopsy with an automated gun. Records were reviewed to determine the frequency with which stereotactic core biopsy obviated a surgical procedure. Cost savings were based on Medicare estimates of $472 for stereotactic core biopsy and $1,335 for surgical biopsy.
RESULTS: Of 31 patients, stereotactic core biopsy revealed carcinoma in 19 (61%), atypical ductal hyperplasia (ADH) in eight (26%), and benign findings discordant with mammographic results in four (13%). Surgical biopsy was recommended for the 12 patients with ADH or benign but discordant core biopsy diagnoses. Of the 19 patients with carcinoma at stereotactic core biopsy, two chose to undergo a second biopsy surgically, two had small foci of ductal carcinoma in situ (DCIS) that would have been fully excised with surgical biopsy, one with DCIS at stereotactic core biopsy underwent axillary dissection after invasion was found at surgery, and one underwent excision but had tumor at lumpectomy margins. Thirteen (42%) of 31 patients were spared a surgical procedure, saving $100 per patient.
CONCLUSION: Stereotactic core biopsy with an automated gun obviated a surgical procedure in 42% of patients with BI-RADS category 5 calcifications, resulting in modest cost savings in this group.

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Year:  1997        PMID: 9169687     DOI: 10.1148/radiology.203.3.9169687

Source DB:  PubMed          Journal:  Radiology        ISSN: 0033-8419            Impact factor:   11.105


  3 in total

1.  Absence of Residual Microcalcifications in Atypical Ductal Hyperplasia Diagnosed via Stereotactic Vacuum-Assisted Breast Biopsy: Is Surgical Excision Obviated?

Authors:  Inyoung Youn; Min Jung Kim; Hee Jung Moon; Eun-Kyung Kim
Journal:  J Breast Cancer       Date:  2014-09-30       Impact factor: 3.588

2.  Association of mammographic density with pathologic findings.

Authors:  Nasrin Ahmadinejad; Samaneh Movahedinia; Sajjadeh Movahedinia; Mona Shahriari
Journal:  Iran Red Crescent Med J       Date:  2013-12-05       Impact factor: 0.611

3.  Microcalcifications Detected as an Abnormality on Screening Mammography: Outcomes and Followup over a Five-Year Period.

Authors:  Melissa Craft; Anne M Bicknell; Georges J Hazan; Karen M Flegg
Journal:  Int J Breast Cancer       Date:  2013-10-01
  3 in total

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